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In oncology, polycythemia vera (PV) is an uncommon myeloproliferative neoplasm in which the bone marrow makes too many red blood cells. [1] The majority of cases [ 2 ] are caused by mutations in the JAK2 gene, most commonly resulting in a single amino acid change in its protein product from valine to phenylalanine at position 617.
Polycythemia vera (PCV) (a.k.a. polycythemia rubra vera (PRV)) occurs when excess red blood cells are produced as a result of an abnormality of the bone marrow. [3] Often, excess white blood cells and platelets are also produced. A hallmark of polycythemia vera is an elevated hematocrit, with Hct > 55% seen in 83% of cases. [19]
Pityriasis rubra pilaris refers to a group of chronic disorders characterized by reddish orange, scaling plaques and keratotic follicular papules. [2]: 442 Symptoms may include reddish-orange patches (Latin: rubra) on the skin, severe flaking (Latin: pityriasis), uncomfortable itching, thickening of the skin on the feet and hands, and thickened bumps around hair follicles (Latin: pilus for hair).
Start with over-the-counter treatments first. For instance, if your skin looks dry, use a gentle moisturizer, Hu advises, and if the rash itches, use an over-the-counter cortisone cream for a week ...
Rosacea is a chronic skin condition that causes redness, flushing, and small bumps on the face that may be pus-filled, swollen, tender, [and] acne-like, says Dr. Kamangar. The rash can occur ...
Miliaria rubra is also known as prickly heat and heat rash. [6] Differential diagnosis should be used to rule out polycythemia vera, which is a rare hematological disorder and appears more often in males than females, generally not before the age of 40. Both disorders share a common trait of appearing after taking a hot shower.
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