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The fourth is a great example of how interactive graphical tools enable a worker involved in sequence analysis to conveniently execute a variety if different computational tools to explore an alignment's phylogenetic implications; or, to predict the structure and functional properties of a specific sequence, e.g., comparative modelling.
The regular paperfolding sequence corresponds to folding a strip of paper consistently in the same direction. If we allow the direction of the fold to vary at each step we obtain a more general class of sequences. Given a binary sequence (f i), we can define a general paperfolding sequence with folding instructions (f i).
Both + Ends-free: P. Aboyoun: 2008 BioPerl dpAlign Dynamic programming: Both: Both + Ends-free: Y. M. Chan: 2003 BLASTZ, LASTZ Seeded pattern-matching: Nucleotide: Local: Schwartz et al. [18] [19] 2004,2009 CUDAlign DNA sequence alignment of unrestricted size in single or multiple GPUs Nucleotide: Local, SemiGlobal, Global: E. Sandes [20] [21 ...
Alignment-free methods can broadly be classified into five categories: a) methods based on k-mer/word frequency, b) methods based on the length of common substrings, c) methods based on the number of (spaced) word matches, d) methods based on micro-alignments, e) methods based on information theory and f) methods based on graphical representation.
wapRNA This is a free web-based application for the processing of high-throughput RNA-Seq data (wapRNA) from next generation sequencing (NGS) platforms, such as Genome Analyzer of Illumina Inc. (Solexa) and SOLiD of Applied Biosystems (SOLiD). wapRNA provides an integrated tool for RNA sequence, refers to the use of High-throughput sequencing ...
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The frequency of a set of k-mers in a species's genome, in a genomic region, or in a class of sequences can be used as a "signature" of the underlying sequence. Comparing these frequencies is computationally easier than sequence alignment and is an important method in alignment-free sequence analysis. It can also be used as a first stage ...
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