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Acute decompensated heart failure (ADHF) is a sudden worsening of the signs and symptoms of heart failure, which typically includes difficulty breathing , leg or feet swelling, and fatigue. [1] ADHF is a common and potentially serious cause of acute respiratory distress. The condition is caused by severe congestion of multiple organs by fluid ...
Heart failure may also be classified as acute or chronic. Chronic heart failure is a long-term condition, usually kept stable by the treatment of symptoms. Acute decompensated heart failure is a worsening of chronic heart failure symptoms, which can result in acute respiratory distress. [66]
The related medication eplerenone was shown in the EPHESUS trial [31] to have a similar effect, and it is specifically labelled for use in decompensated heart failure complicating acute myocardial infarction. While the antagonism of aldosterone will decrease the effects of sodium and water retention, it is thought that the main mechanism of ...
CXL 1020 is an experimental drug that is being investigated as a treatment for acute decompensated heart failure.CXL 1020 functions as a nitroxyl donor; nitroxyl is the reduced, protonated version of nitric oxide. [1]
acute cardiogenic shock or acute decompensation of chronic heart failure: Type 2 (chronic CRS) Chronic abnormalities in heart function: progressive chronic kidney disease: chronic heart failure: Type 3 (acute renocardiac syndrome) Abrupt worsening of kidney function: acute cardiac disorder (e.g. heart failure, abnormal heart rhythm, or ...
Heart failure - Giving 2.5 times of previous oral dose twice daily for those with acute decompensated heart failure is a reasonable strategy. However, daily assessment of clinical response is needed to adjust the subsequent doses. [6] Edema - Volume overload associated with liver cirrhosis, heart failure, or nephrotic syndrome [11]
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