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Diltiazem, sold under the brand name Cardizem among others, is a nondihydropyridine calcium channel blocker medication used to treat high blood pressure, angina, and certain heart arrhythmias. [9] It may also be used in hyperthyroidism if beta blockers cannot be used. [ 9 ]
Other potential symptoms include: nausea and vomiting, a decreased level of consciousness, and breathing difficulties. [2] Symptoms usually begin within 6 hours of taking the medication by mouth. [2] With extended release formulations symptoms may not occur for up to a day. [2] Seizures are rare in adults but in children occur more often. [2]
[7] [15] Some Kawasaki-like symptoms that may be present (especially in children under the age of 5) [49] include mucosal changes around the mouth ("strawberry tongue", cracked lips, etc.), red eyes (conjunctivitis without pus), widespread rash (consistent with leukocytoclastic vasculitis [51]), red or swollen hands and feet, and enlarged lymph ...
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The Pediatric Symptom Checklist (PSC) is a 35-item parent-report questionnaire designed to identify children with difficulties in psychosocial functioning. Its primary purpose is to alert pediatricians at an early point about which children would benefit from further assessment. [1]
Understanding commonly prescribed drugs allows healthcare professionals to react to symptoms quickly and new treatment strategies can be developed. However, the data for commonly prescribed drugs may be outdated due to the time lag between data collection and publication as well as errors in data collection process.
Globally, the prevalence of PBD in children and adolescents under the age of 18 is estimated at 3.9% as of 2019. [21] [25] However, 5 surveys (from Brazil, England, Turkey, and the United States) have reported pre-adolescence rates of PBD as zero or close to zero. [25]
Hepatotoxicity (from hepatic toxicity) implies chemical-driven liver damage. Drug-induced liver injury (DILI) is a cause of acute and chronic liver disease caused specifically by medications and the most common reason for a drug to be withdrawn from the market after approval.