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Hypofrontality is a symptom of numerous neurological diseases defined as reduced utilization of glucose and blood flow in the prefrontal cortex. Hypofrontality can be difficult to detect under resting conditions, but under cognitive challenges, it has been seen to correlate with memory deficits along with executive function deficits.
It is indicated that the common hypofrontality (underactivation of frontal brain regions) and cortical activation pattern induced by serotonergic and glutamatergic hallucinogens is due to a common disruption of thalamic gating of sensory and cognitive information. The CSTC feedback loop plays a major role in gating or filtering out external and ...
Dysexecutive syndrome (DES) consists of a group of symptoms, [1] usually resulting from brain damage, that fall into cognitive, behavioural and emotional categories and tend to occur together.
Transient global amnesia (TGA) is an uncommon condition affecting about 1 in every 20,000 Americans, although as many as 1 of every 4,000 over age 50. Many TGA patients have a precipitating factor ...
Frontal lobe disorder, also frontal lobe syndrome, is an impairment of the frontal lobe of the brain due to disease or frontal lobe injury. [5] The frontal lobe plays a key role in executive functions such as motivation, planning, social behaviour, and speech production.
Transient global amnesia is a dramatic, sudden, temporary, near-total loss of short-term memory. Various causes have been hypothesized including ischemia, epilepsy, migraine [ 160 ] and disturbance of cerebral venous blood flow, [ 161 ] leading to ischemia of structures such as the hippocampus that are involved in memory.
The orbitofrontal cortex (OFC) is a prefrontal cortex region in the frontal lobes of the brain which is involved in the cognitive process of decision-making.In non-human primates it consists of the association cortex areas Brodmann area 11, 12 and 13; in humans it consists of Brodmann area 10, 11 and 47.
Transient loss of consciousness (TLOC) is a brief period of unconsciousness which resolves spontaneously. It may be traumatic—as in a concussion —or non-traumatic in origin. Common causes of non-traumatic TLOC include syncope and epileptic seizures .