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Celecoxib, sold under the brand name Celebrex among others, is a COX-2 inhibitor and nonsteroidal anti-inflammatory drug (NSAID). [7] It is used to treat the pain and inflammation in osteoarthritis, acute pain in adults, rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, painful menstruation, and juvenile rheumatoid arthritis. [7]
The National Cancer Institute has done some studies on COX-2 and cancer. [12] COX-2 can act as an anti-tumor enzyme, but only in specific cases. [13] The FDA has approved Celebrex for treatment of familial adenomatous polyposis (FAP). [14] COX-2 inhibitors are currently being studied in breast cancer [15] and appear to be beneficial. [16]
The widespread use of NSAIDs has meant that the adverse effects of these drugs have become increasingly common. Use of NSAIDs increases risk of a range of gastrointestinal (GI) problems, kidney disease and adverse cardiovascular events. [40] [41] As commonly used for post-operative pain, there is evidence of increased risk of kidney ...
This is an accepted version of this page This is the latest accepted revision, reviewed on 18 January 2025. Medical condition Kidney cancer Other names Renal cancer Micrograph showing the most common type of kidney cancer (clear cell renal cell carcinoma). H&E stain. Specialty Oncology nephrology Urology Symptoms Blood in the urine, lump in the abdomen, back pain Usual onset After the age of ...
Prostaglandin inhibitors are drugs that inhibit the synthesis of prostaglandin in human body. [1] There are various types of prostaglandins responsible for different physiological reactions such as maintaining the blood flow in stomach and kidney, regulating the contraction of involuntary muscles and blood vessels, and act as a mediator of inflammation and pain.
Kidney disease. CDC. 10 Signs You May Have Kidney Disease. National Kidney Foundation. Aging and kidney disease. National Kidney Foundation. Kidney Transplant Outcomes in Recipients Over the Age ...
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