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Histopathological image of dyshidrotic dermatitis, showing focal spongiotic change in the epidermis. Spongiosis is mainly intercellular [1] edema (abnormal accumulation of fluid) in the epidermis, [2] and is characteristic of eczematous dermatitis, manifested clinically by intraepidermal vesicles (fluid-containing spaces), "juicy" papules, and/or lichenification. [3]
A non-specific histologic examination reveals superficial spongiotic dermatitis connected to a hair follicle and the surrounding epidermis. A mention of exocytosis is made in the spongiotic region. Inflammatory cells are present in the subadjacent dermis, while the deeper dermis is unaffected. [2]
The spongiosis is mild to absent; Pronounced irregular acanthosis, hyperkeratosis, and parakeratosis; Minimal dermal inflammation and exocytosis of inflammatory cells are present. Possibly fibrosis of papillary dermis; PAS stain is essential to exclude fungal infection. [2] Subacute Allergic/contact dermatitis or atopic dermatitis As above.
Eczema refers to a broad range of conditions that begin as spongiotic dermatitis and may progress to a lichenified stage. Pages in category "Eczema" The following 44 pages are in this category, out of 44 total.
Patch testing may be considered if there is suspicion of allergic contact dermatitis. [2] A skin biopsy is rarely necessary, [2] but if done mostly shows an interstitial granulomatous dermatitis, some lesions being spongiotic. [4] Id reactions cannot be distinguished from other skin diseases by histopathology.
Micrograph of Schamberg disease, suggesting the spongiotic stage of a purpuric dermatitis. Additional testing may aid diagnosis. A skin biopsy may be taken to determine capillaritis of dermal vessels. [8] Capillaritis or pigmented purpura is skin condition that has brown-reddish patches on the skin, which is caused by leaky capillaries. [9]
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Lichen simplex chronicus (LSC) is thick leathery skin with exaggerated skin markings caused by sudden itching and excessive rubbing and scratching. [1] It generally results in small bumps, patches, scratch marks and scale. [1]
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