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Roseola, also known as sixth disease, is an infectious disease caused by certain types of human herpes viruses. [2] Most infections occur before the age of three. [ 1 ] Symptoms vary from absent to the classic presentation of a fever of rapid onset followed by a rash.
Primary infection with this virus is the cause of the common childhood illness exanthema subitum (also known as roseola infantum or sixth disease). Additionally, reactivation is common in transplant recipients, which can cause several clinical manifestations such as encephalitis , bone marrow suppression, and pneumonitis .
[1] [2] Both rubella, also known as German measles, and roseola are different diseases caused by unrelated viruses. [15] Symptoms usually develop 10–12 days after exposure to an infected person and last 7–10 days. [7] [8] Initial symptoms typically include fever, often greater than 40 °C (104 °F), cough, runny nose, and inflamed eyes.
The acquisition of HHV-6 in infancy is often symptomatic, resulting in childhood fever, diarrhea, and exanthem subitum rash (commonly known as roseola). Although rare, this initial infection can also cause febrile seizures , encephalitis or intractable seizures.
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Roseola vaccinia is a cutaneous condition characterized by a prominent rim of erythema surrounding the site of vaccinia injection. [1]: 393 ...
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