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  2. Hepatotoxicity - Wikipedia

    en.wikipedia.org/wiki/Hepatotoxicity

    Drug-induced liver injury (DILI) is a cause of acute and chronic liver disease caused specifically by medications and the most common reason for a drug to be withdrawn from the market after approval. The liver plays a central role in transforming and clearing chemicals and is susceptible to the toxicity from these agents.

  3. Hepatotoxin - Wikipedia

    en.wikipedia.org/wiki/Hepatotoxin

    A hepatotoxin (Gr., hepato = liver) is a toxic chemical substance that damages the liver.. It can be a side-effect, but hepatotoxins are also found naturally, such as microcystins and pyrrolizidine alkaloids, or in laboratory environments, such as carbon tetrachloride, or far more pervasively in the form of ethanol (drinking alcohol).

  4. List of antineoplastic agents - Wikipedia

    en.wikipedia.org/wiki/List_of_antineoplastic_agents

    Myelosupression, embryo-fetal toxicity, hepatotoxicity (rare) [19] Trabectedin: IV Alkylates DNA. Advanced liposarcoma and leimyosarcoma Bone marrow suppression, rhabdomyolysis, embryo-fetal toxicity, capillary leak syndrome, hepatotoxicity [20] 1.10 Platinum compounds: Carboplatin: IV: Reacts with DNA, inducing apoptosis, non-cell cycle specific.

  5. List of withdrawn drugs - Wikipedia

    en.wikipedia.org/wiki/List_of_withdrawn_drugs

    Renal toxicity, animal carcinogenicity. [3] Bezitramide: 2004 Netherlands Risk of fatal overdose [10] Bithionol: 1967 US Dermatologic toxicity. [3] Brotizolam: 1989 UK Animal carcinogenicity. [3] Bromfenac: 1998 US Severe hepatitis and liver failure (requiring transplantation). [2] Bucetin: 1986 Germany Kidney damage [3] Buformin: 1978 Germany ...

  6. List of herbs with known adverse effects - Wikipedia

    en.wikipedia.org/wiki/List_of_herbs_with_known...

    Liver toxicity, allergic reaction, anaphylaxis [3] Kava: awa, kava-kava [4] Piper methysticum: Potentiates CNS sedatives, [3] chronic use might cause a reversible dry skin condition. [18] Khat: qat Catha edulis: Chronic liver dysfunction [3] [19] Kratom: Mitragyna speciosa: Hepatotoxicity [20] [19] Liquorice root Glycyrrhiza glabra

  7. Imidazopyridine - Wikipedia

    en.wikipedia.org/wiki/Imidazopyridine

    SCH28080—the prototypical potassium-competitive acid blocker which has not found clinical use because of liver toxicity in animal trials and elevated liver enzyme activity in the serum of human volunteers. [7] Imidazo[4,5-b]pyridines: Tenatoprazole—it blocks the gastric proton pump leading to decline of gastric acid production.