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Spironolactone is a once-a-day tablet that can stop hair loss from progressing and encourage new hair growth. It’s especially useful for women with hormonal issues like PCOS. It may take six to ...
The AR antagonism of spironolactone mostly underlies its antiandrogenic activity and is the major mechanism responsible for its therapeutic benefits in the treatment of androgen-dependent conditions like acne, hirsutism, and pattern hair loss and its usefulness in hormone therapy for transgender women.
Spironolactone can be used in the treatment of female-pattern hair loss (pattern scalp hair loss in women). [69] There is tentative low quality evidence supporting its use for this indication. [70] Although apparently effective, not all cases of female-pattern hair loss are dependent on androgens. [71]
While the FDA hasn’t approved oral minoxidil for hair loss, clinical trials have shown it’s quite effective for hair growth at various doses (0.25 to 2.5 mg daily). Spironolactone .
Minoxidil, applied topically, is widely used for the treatment of hair loss. It may be effective in helping promote hair growth in both men and women with androgenic alopecia. [20] [21] About 40% of men experience hair regrowth after 3–6 months. [22] It is the only topical product that is FDA approved in America for androgenic hair loss. [20]