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TMP/SMX is commonly used due to its ability to achieve high concentrations in urinary tract tissues and urine. This antibiotic combination demonstrates notable efficacy in both the treatment and prophylaxis of recurrent urinary tract infections. [12] Common adverse effects include nausea, vomiting, rash,pruritus, and photosensitivity. [26]
Fosfomycin can be used as an efficacious treatment for both UTIs and complicated UTIs including acute pyelonephritis. The standard regimen for complicated UTIs is an oral 3 g dose administered once every 48 or 72 hours for a total of 3 doses or a 6 g dose every 8 hours for 7–14 days when fosfomycin is given in IV form.
A urinary tract infection (UTI) is an infection that affects a part of the urinary tract. [1] Lower urinary tract infections may involve the bladder ( cystitis ) or urethra ( urethritis ) while upper urinary tract infections affect the kidney ( pyelonephritis ). [ 10 ]
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Urinary tract infections, bacterial prostatitis, community-acquired pneumonia, bacterial diarrhea, mycoplasmal infections, gonorrhea: Nausea (rare), irreversible damage to central nervous system (uncommon), tendinosis (rare) Inhibits the bacterial DNA gyrase or the topoisomerase IV enzyme, thereby inhibiting DNA replication and transcription ...
This leads to infection in the bladder, kidneys, and other organs connected to the urinary tract. [ 4 ] CAUTI can lead to complications such as prostatitis , epididymitis , and orchitis in men, and cystitis, pyelonephritis , gram-negative bacteremia , endocarditis , vertebral osteomyelitis , septic arthritis , endophthalmitis , and meningitis ...
Risk factors include sexual intercourse, prior urinary tract infections, diabetes, structural problems of the urinary tract, and spermicide use. [2] [3] The mechanism of infection is usually spread up the urinary tract. [2] Less often infection occurs through the bloodstream. [1] Diagnosis is typically based on symptoms and supported by ...
The first guideline for diagnosis and treatment of interstitial cystitis is released by a Japanese research team in 2009. [71] The American Urological Association released the first American clinical practice guideline for diagnosing and treating IC/BPS in 2011 and has since (in 2014 and 2022) updated the guideline to maintain standard of care ...
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