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Dextromethorphan, sold under the brand name Robitussin among others, is a cough suppressant used in many cough and cold medicines. [6] In 2022, the US Food and Drug Administration (FDA) approved the combination dextromethorphan/bupropion to serve as a rapid-acting antidepressant in people with major depressive disorder.
Guaifenesin might act as an expectorant by increasing the volume and reducing the viscosity of secretions in the trachea and bronchi via stimulation of the gastric mucosa. . This stimulation leads to an increased parasympathetic activity in the respiratory tract via the so-called gastro-pulmonary reflex, although some in vitro studies suggested that it might also act directly on the ...
The third and fourth plateaus (7.5 mg/kg and over) cause profound alterations in consciousness, and users often report out-of-body experiences or temporary psychosis. [ 15 ] [ 16 ] This results in a sort of flanging (speeding up and/or slowing down) of sensory input, which is another characteristic effect of recreational use.
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Mucinex is not (or is no longer) the only form of extended release guaifenesin tablets available in the United States. I have personally purchased (October, 2013) at Walgreen Drugs, their store brand of "Mucus Relief" 12-hour, extended-release 600mg guaifenesin tablets.AnClarTex 18:57, 3 October 2013 (UTC)
Pseudoephedrine acts on α- and β 2-adrenergic receptors, to cause vasoconstriction and relaxation of smooth muscle in the bronchi, respectively. [88] [89] α-Adrenergic receptors are located on the muscles lining the walls of blood vessels. When these receptors are activated, the muscles contract, causing the blood vessels to constrict ...
Chlorpromazine, an antipsychotic and antiemetic drug which is classed as a "major" tranquilizer, may cause paradoxical effects such as agitation, hallucinations, excitement, insomnia, bizarre dreams, aggravation of psychotic symptoms and toxic confusional states. [8] These may be more common in elderly dementia patients.