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Acute esophageal necrosis (AEN), black esophagus, or Gurvits syndrome is a rare esophageal disorder. AEN defines itself with dark pigmentation of the esophagus , found during an upper gastrointestinal endoscopy . [ 2 ]
Spores of C. novyi escape from the gut and lodge in the liver, where they remain dormant until some injury creates anaerobic conditions for them to germinate, causing local necrosis and widespread damage to the microvascular system, resulting in subcutaneous bleeding and blackening of the skin, hence the common name "black disease".
Initial skin findings include red-purple, dusky, flat spots known as macules that start on the trunk and spread out from there. These skin lesions then transform into large blisters. The affected skin can then become necrotic or sag from the body and peel off in great swaths. [7]
Necrosis can also result from chemical trauma, with alkaline and acidic compounds causing liquefactive and coagulative necrosis, respectively, in affected tissues. The severity of such cases varies significantly based on multiple factors, including the compound concentration, type of tissue affected, and the extent of chemical exposure.
An eschar (/ ˈ ɛ s k ɑːr /; Greek: ἐσχάρᾱ, romanized: eskhara; Latin: eschara) is a slough [1] or piece of dead tissue that is cast off from the surface of the skin, particularly after a burn injury, but also seen in gangrene, ulcer, fungal infections, necrotizing spider bite wounds, tick bites associated with spotted fevers and exposure to cutaneous anthrax.
At only 33, this is Megan Fry's fourth bout with skin cancer. She hopes her story encourages others to learn how to spot and get treatment for basal cell cancer. Overnight, her mole turned black ...
Overview. Acne is a skin condition characterized by clogged pores. When pores get clogged, it causes red lesions — which you know as pimples — to form on the face or other areas of the body ...
Necrotizing fasciitis (NF), also known as flesh-eating disease, is an infection that kills the body's soft tissue. [3] It is a serious disease that begins and spreads quickly. [3] Symptoms include red or purple or black skin, swelling, severe pain, fever, and vomiting. [3] The most commonly affected areas are the limbs and perineum. [2]