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The formulation and manufacturing processes of topical gels are relatively simpler and more cost effective than other semisolid dosage forms. [5] [1] [8] The release profile of the gel can be modified by altering the properties of the gelator, allowing for continuous drug delivery. [1] Topical gels are also eco-friendly, biocompatible and ...
Figure 1.0 - Basic anatomical features of the human eye. Ophthalmic drug administration is the administration of a drug to the eyes, most typically as an eye drop formulation. Topical formulations are used to combat a multitude of diseased states of the eye. These states may include bacterial infections, eye injury, glaucoma, and dry eye. [1]
A medical professional administering nose drops Instillation of eye drops. A topical medication is a medication that is applied to a particular place on or in the body. Most often topical medication means application to body surfaces such as the skin or mucous membranes to treat ailments via a large range of classes including creams, foams, gels, lotions, and ointments. [1]
It is also used to reduce redness of the eye. [3] The gel is indicated for the topical treatment of persistent (nontransient) facial erythema of rosacea in adults 18 years of age or older. [2] A 2017 Cochrane review found insufficient evidence to determine if brimonidine slows optic nerve damage. [12]
[23] [24] [25] Because of their mucoadhesive properties, thiolated polymers are an effective tool in the treatment of diseases such as dry eye, dry mouth, and dry vagina syndrome where dry mucosal surfaces are involved. [26] [27] [28]
An advantage of a transdermal drug delivery route over other types of medication delivery (such as oral, topical, intravenous, or intramuscular) is that the patch provides a controlled release of the medication into the patient, usually through either a porous membrane covering a reservoir of medication or through body heat melting thin layers ...