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The molecular disease concept put forward in the 1949 paper also became the basis for Linus Pauling's view of evolution. In the 1960s, by which time it had been shown that sickle cell trait confers resistance to malaria and so the gene had both positive and negative effects and demonstrated heterozygote advantage , Pauling suggested that ...
The Linus Pauling Institute still exists, but moved in 1996 from Palo Alto, California, to Corvallis, Oregon, where it is part of the Linus Pauling Science Center at Oregon State University. [ 181 ] [ 182 ] [ 183 ] The Valley Library Special Collections at Oregon State University contain the Ava Helen and Linus Pauling Papers, including ...
Vitamin C and the Common Cold is a popular book by Linus Pauling, first published in 1970, on vitamin C, its interactions with common cold and the role of vitamin C megadosage in human health. [1] The book promoted the idea that taking large amounts of vitamin C could reduce the duration and severity of the common cold .
Since the first claims of medical breakthroughs with vitamin C by Pauling and others, findings on the health effects of vitamin C have been controversial and contradictory. [33] [34] Pauling's claims have been criticised as overbroad. [35] Later research branched out into nutrients besides niacin and vitamin C, including essential fatty acids. [36]
In collaboration with Linus Pauling, Itano used electrophoresis to demonstrate the difference between normal hemoglobin and sickle cell hemoglobin; their 1949 paper "Sickle Cell Anemia, a Molecular Disease" (coauthored also with S. J. Singer and Ibert C. Wells) [2] was a landmark in both molecular medicine and protein electrophoresis, though ...
Another paper in Science by Pauling in 1968, [8] introduced and defined this view of molecular medicine that focuses on natural and nutritional substances used for treatment and prevention. Published research and progress was slow until the 1970s' "biological revolution" that introduced many new techniques and commercial applications. [9]
Although Linus Pauling was known for highly respectable research in chemistry and biochemistry, he was also known for promoting the consumption of vitamin C in large doses. [25] Although he claimed and stood firm in his claim that consuming over 1,000 mg is helpful for one’s immune system when fighting a head cold, the results of empirical ...
Linus Pauling published in 1931 his landmark paper on valence bond theory: "On the Nature of the Chemical Bond". Building on this article, Pauling's 1939 textbook: On the Nature of the Chemical Bond would become what some have called the bible of modern chemistry. This book helped experimental chemists to understand the impact of quantum theory ...