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Cocaine increases alertness, feelings of well-being, euphoria, energy, sociability, and sexuality. The former are some of the desired effects of cocaine intoxication. Not having the normal use of mental faculties by reason of the introduction of cocaine is defined drug intoxication by the laws in America, Europe, and most of the rest of the World, and it is a serious crime in specific contexts ...
Toxic leukoencephalopathy is a rare condition that is characterized by progressive damage (-pathy) to white matter (-leuko-) in the brain (-encephalo-), particularly myelin, due to causes such as exposure to substance use, environmental toxins, or chemotherapeutic drugs. The prevalence of this disease is infrequent and often goes unreported ...
Alcohol can exacerbate the symptoms and may directly contribute to increased severity of symptoms. The reasons for toxicity vary depending on the mixture of drugs. Usually, most victims die after using two or more drugs in combination that suppress breathing, and the low blood oxygen level causes brain death.
In general, it is the exposure of a given tissue to drug (i.e. drug concentration over time), rather than dose, that drives the pharmacological and toxicological effects. For example, at the same dose there may be marked inter-individual variability in exposure due to polymorphisms in metabolism, DDIs or differences in body weight or ...
There are a few possible side effects linked to taking NSAIDs, including: gastrointestinal problems (such as irritation, ulcers, or bleeding), increased risk of heart attack and stroke, reduced ...
In the U.S., buprenorphine is mainly sold under the brand name Suboxone, in which form it’s combined with naloxone, the drug that can reverse the effects of an overdose. If someone tries to misuse Suboxone by injecting it, the predominant effect will be that of the naloxone, not the buprenorphine.
Just before 3 p.m., seven deputies were taken to local hospitals as a precaution after experiencing symptoms potentially related to today’s earlier suspected overdose incident, the sheriff's ...
Researchers, whose work was published in Sleep in October, looked into the effects of a "typical dose" and a "high dose" of caffeine consumed at different times of the day ("morning, afternoon ...