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Although no cat is completely allergy-free, some breeds are less likely to cause those pesky symptoms (sneezing, itching, sniffling, watery eyes, you know the drill).
Fel d 1 is the most prominent cat allergen, accounting for 96% of human cat allergies. [4] The remaining cat allergens are Fel d 2–8, [5] with Fel d 4, a major urinary protein found in the saliva of cats, [6] occurring the most in humans among the other seven allergens. All cats produce Fel d 1, including hypoallergenic cats.
Fel d 1 is a secretoglobin protein complex that, in cats, is encoded by the CH1 (chain 1/Fel d 1-A) and CH2 (chain 2/Fel d 1-B) genes. [2] [3] Among cats, Fel d 1 is produced largely in their saliva and by the sebaceous glands located in their skin. It is the primary allergen present on cats and kittens.
The Siberian cat is described in the book under its former name, the "Russian Long-haired Cat". [4] [21] However, in the preface of the 1892 edition, Weir also mentions a cat he refers to as a "Siberian Cat": [22] I have been shown a Siberian Cat, by Mr. Castang, of Leadenhall Market; the breed is entirely new to me.
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The Neva Masquerade cat on a 2020 Russian stamp. The Neva Masquerade is a specific colorway of semi long-haired Siberian Forest domestic cat, which originates in Russia. [1] [2] It is not the sister breed [3] or colourpoint variant of the Siberian cat, a centuries-old Russian landrace.
While there are references to Russia’s native forest cats dating back to 1,000 AD, it was not until 1987 that the Russians drew up the first official breed standard.
The proteins that cause allergies (mainly Fel d 1 in cats and Can f 1 in dogs) are found not only in the animals' fur or hair but also in saliva, urine, mucus, and hair roots and in the dander sloughed from the animals' skin. Thus, the widespread idea that "hypoallergenic pets" are those that have less hair or shed less is a myth.