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Asthma phenotyping and endotyping has emerged as a novel approach to asthma classification inspired by precision medicine which separates the clinical presentations of asthma, or asthma phenotypes, from their underlying causes, or asthma endotypes. The best-supported endotypic distinction is the type 2-high/type 2-low distinction.
What causes asthma? While the exact cause of asthma is unknown, "certain genetic factors can increase the risk of developing the disease," says Avner. For example, she explains that if a parent ...
Asthma triggers are factors or stimuli that provoke the exacerbation of asthma symptoms or increase the degree of airflow disruption, which can lead to an asthma attack. [1] An asthma attack is characterized by an obstruction of the airway , hypersecretion of mucus and bronchoconstriction due to the contraction of smooth muscles around the ...
GERD may be common in difficult-to-control asthma, but according to one study, treating it does not seem to affect the asthma. [33] When there is a clinical suspicion for GERD as the cause of the asthma, an Esophageal pH Monitoring is required to confirm the diagnosis and establish the relationship between GERD and asthma.
Genetics alone doesn’t cause asthma. Dr. Hamzavi says it’s often a combination of factors, including family history, environment and lifestyle—all elements that can also worsen asthma.
Dry air easily dries out the airways, leading to irritation that can cause swelling and other asthma symptoms. Cold air also causes more histamine production, which is what the body makes during ...