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The peduncle is not part of the lateral-spinothalamic-tract-pathway; the medulla receives the info and passes it onto the peduncle from elsewhere (see somatosensory system). The thalamus is where pain is thought to be brought into perception ; it also aids in pain suppression and modulation, acting like a bouncer , allowing certain intensities ...
' pain receptor ') is a sensory neuron that responds to damaging or potentially damaging stimuli by sending "possible threat" signals [1] [2] [3] to the spinal cord and the brain. The brain creates the sensation of pain to direct attention to the body part, so the threat can be mitigated; this process is called nociception .
Descending pathways also activate opioid receptor-containing parts of the spinal cord. [citation needed] Afferent pathways interfere with each other constructively, so that the brain can control the degree of pain that is perceived, based on which pain stimuli are to be ignored to pursue potential gains.
The pathway crosses over at the level of the spinal cord, rather than in the brainstem like the dorsal column-medial lemniscus pathway and lateral corticospinal tract. It is one of the three tracts which make up the anterolateral system : anterior and lateral spinothalamic tract, spinotectal tract , spinoreticular tract .
The tract transmits slow nociceptive/pain information (but thermal, and crude touch information as well) from the spinal cord to reticular formation which in turn relays the information to the thalamus via reticulothalamic fibers as well as to other parts of the brain (as opposed to the spinothalamic tract - the direct pathway of the ...
Another type of pain, known as neuropathic pain, is caused by a direct problem or disease that affects the nerves in the central nervous system. [11] The sensory pathways the WDR neurons can play a role in. A subset of this neuropathic pain, known as chronic neuropathic pain, is characterized by its long lasting and high pain intensity.
The first-order axons make contact with second-order neurons of the dorsal column nuclei (the gracile nucleus and the cuneate nucleus) in the lower medulla. The second-order neurons send their axons to the thalamus. The third-order neurons are in the ventral posterolateral nucleus in the thalamus and fibres from these ascend to the postcentral ...
Descartes' pain pathway: "Particles of heat" (A) activate a spot of skin (B) attached by a fine thread (cc) to a valve in the brain (de) where this activity opens the valve, allowing the animal spirits to flow from a cavity (F) into the muscles causing them to flinch from the stimulus, turn the head and eyes toward the affected body part, and ...