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Radial glial cells, or radial glial progenitor cells (RGPs), are bipolar-shaped progenitor cells that are responsible for producing all of the neurons in the cerebral cortex. RGPs also produce certain lineages of glia , including astrocytes and oligodendrocytes .
Radial glial cells, also called radial glial progenitor cells, divide asymmetrically to produce a neuroblast and another radial glial cell that will re-enter the cell cycle. [5] [3] This mitosis occurs in the germinal neuroepithelium (or germinal zone), when a radial glial cell divides to produce the neuroblast. The neuroblast detaches from the ...
Glia, also called glial cells ... the cerebellum and retina retain characteristic radial glial cells. ... in cognitive processes like learning and memory. [49] ...
Neuroepithelial cells symmetrically divide or differentiate into progenitor cells called radial glial cells in asymmetric cell division. These can further differentiate into neurons or glial cells. Neuroepithelial cells are a class of stem cell and have the ability to self-renew.
These early stem cells are called neuroepithelial cells (NEC)s, but soon take on a highly elongated radial morphology and are then known as radial glial cells (RGC)s. [3] RGCs are the primary stem cells of the mammalian CNS, and reside in the embryonic ventricular zone , which lies adjacent to the central fluid-filled cavity ( ventricular ...
Foot-like processes are also present in Müller glia (modified astrocytes of the retina), [3] pancreatic stellate cells, [4] dendritic cells, [5] oligodendrocytes, [6] and others. Microglia , which are notably smaller than macroglia , can also extend their end-processes to contact areas of capillaries that are devoid of astrocyte endfeet , and ...
The radial glial cells are disposed in planes perpendicular to the axes of ventricles. One of their processes abuts the pia mater , while the other is deeply buried in gray matter. Radial glia are mostly present during development, playing a role in neuron migration .
The primary neural stem cells of the brain and spinal cord, termed radial glial cells, instead reside in the ventricular zone (VZ) (so-called because the VZ lines the inside of the developing ventricles). [4]