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Reference ranges for blood tests of plasma renin activity can be given both in mass and in international units (μIU/mL or equivalently mIU/L, improperly shown as μU/mL or U/L, confusing mcU/mL used where Greek μ not available), with the former being roughly convertible to the latter by multiplying with 11.2. [3]
0.6–5.6 pg/mL: 2.1–19.4 pmol/L 14–15 years: 2.7–112.3 pg/mL: 9.4–389.7 pmol/L: 1.0–6.2 pg/mL: 3.5–21.5 pmol/L 16–17 years: 31.5–159 pg/mL: 109.3 ...
Insulin is given in μU/mL. [7] Glucose and insulin are both during fasting. [2] This model correlated well with estimates using the euglycemic clamp method (r = 0.88). [2] The authors have tested HOMA and HOMA2 extensively against other measures of insulin resistance (or its reciprocal, insulin sensitivity) and β-cell function. [4] [8] [9]
For example, on a certain monitor, the horizontal distance between the upper limits for parathyroid hormone in pmol/L and pg/mL may be 7 cm, with the mass concentration to the right. A molar concentration of, for example, 5 pmol/L would therefore correspond to a mass concentration located 7 cm to the right in the mass diagram, that is ...
The blood insulin level can be measured in international units, such as μIU/mL or in molar concentration, such as pmol/L, where 1 μIU/mL equals 6.945 pmol/L. [64] A typical blood level between meals is 8–11 μIU/mL (57–79 pmol/L). [65]
If high levels (7.5 mg/min or higher) are needed, the patient is considered insulin-sensitive. Conversely, very low levels (4.0 mg/min or lower) indicate insulin resistance. Levels falling between 4.0 and 7.5 mg/min are not conclusive and suggest "impaired glucose tolerance," which is an early indication of insulin resistance. [54]
1 IU of rhEGF is defined as the potency of 0.001 μg of a rhEGF in the "91/530" standard vial. One manufacturer reports that its rhEGF is 1.4 times as potent as the 91/530 standard. [7] 12.5 IU of oxytocin is defined as the potency of 21 μg of pure peptide in the "76/575" standard vial. [8]
Proprotein convertase 2 (PC2) also known as prohormone convertase 2 or neuroendocrine convertase 2 (NEC2) is a serine protease and proprotein convertase PC2, like proprotein convertase 1 (PC1), is an enzyme responsible for the first step in the maturation of many neuroendocrine peptides from their precursors, such as the conversion of proinsulin to insulin intermediates.
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