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  2. List of sequenced eukaryotic genomes - Wikipedia

    en.wikipedia.org/wiki/List_of_sequenced...

    Saccharomyces cerevisiae was the first eukaryotic organism to have its complete genome sequence determined.. This list of "sequenced" eukaryotic genomes contains all the eukaryotes known to have publicly available complete nuclear and organelle genome sequences that have been sequenced, assembled, annotated and published; draft genomes are not included, nor are organelle-only sequences.

  3. Whole genome sequencing - Wikipedia

    en.wikipedia.org/wiki/Whole_genome_sequencing

    The genome sequence of a single cell selected from a mixed population of cells can be determined using techniques of single cell genome sequencing. This has important advantages in environmental microbiology in cases where a single cell of a particular microorganism species can be isolated from a mixed population by microscopy on the basis of ...

  4. Genome project - Wikipedia

    en.wikipedia.org/wiki/Genome_project

    For a bacterium containing a single chromosome, a genome project will aim to map the sequence of that chromosome. For the human species, whose genome includes 22 pairs of autosomes and 2 sex chromosomes, a complete genome sequence will involve 46 separate chromosome sequences. The Human Genome Project is a well known example of a genome project ...

  5. Coverage (genetics) - Wikipedia

    en.wikipedia.org/wiki/Coverage_(genetics)

    Sequence coverage (or depth) is the number of unique reads that include a given nucleotide in the reconstructed sequence. [1] [2] Deep sequencing refers to the general concept of aiming for high number of unique reads of each region of a sequence. [3] Physical coverage, the cumulative length of reads or read pairs expressed as a multiple of ...

  6. Genomics - Wikipedia

    en.wikipedia.org/wiki/Genomics

    Genomics is an interdisciplinary field of molecular biology focusing on the structure, function, evolution, mapping, and editing of genomes.A genome is an organism's complete set of DNA, including all of its genes as well as its hierarchical, three-dimensional structural configuration.

  7. Genomic library - Wikipedia

    en.wikipedia.org/wiki/Genomic_library

    This map provides sequences of known distances apart, which can be used to help with the assembly of sequence reads acquired through shotgun sequencing. [4] The human genome sequence, which was declared complete in 2003, was assembled using both a BAC library and shotgun sequencing. [18] [19]

  8. Sequencing - Wikipedia

    en.wikipedia.org/wiki/Sequencing

    The major advantage of this approach is the complete sequencing set can be performed in a single reaction, rather than the four needed with the labeled-primer approach. This is accomplished by labelling each of the dideoxynucleotide chain-terminators with a separate fluorescent dye, which fluoresces at a different wavelength .

  9. Read (biology) - Wikipedia

    en.wikipedia.org/wiki/Read_(biology)

    A genome is the complete genetic information of an organism or a cell. Single or double stranded nucleic acids store this information in a linear or in a circular sequence. To precisely determine this sequence, over time more efficient technologies with increased accuracy, throughput and sequencing speed have been developed.