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  2. Causes of cancer - Wikipedia

    en.wikipedia.org/wiki/Causes_of_cancer

    The basic cause of sporadic (non-familial) cancers is DNA damage and genomic instability. [1] [2] A minority of cancers are due to inherited genetic mutations. [3] Most cancers are related to environmental, lifestyle, or behavioral exposures. [4] Cancer is generally not contagious in humans, though it can be caused by oncoviruses and cancer ...

  3. Carcinogenesis - Wikipedia

    en.wikipedia.org/wiki/Carcinogenesis

    The central role of DNA damage and epigenetic defects in DNA repair genes in carcinogenesis. DNA damage is considered to be the primary cause of cancer. [17] More than 60,000 new naturally-occurring instances of DNA damage arise, on average, per human cell, per day, due to endogenous cellular processes (see article DNA damage (naturally occurring)).

  4. Cancer - Wikipedia

    en.wikipedia.org/wiki/Cancer

    Tobacco smoke, for example, causes 90% of lung cancer. [48] Tobacco use can cause cancer throughout the body including in the mouth and throat, larynx, esophagus, stomach, bladder, kidney, cervix, colon/rectum, liver and pancreas. [49] [50] Tobacco smoke contains over fifty known carcinogens, including nitrosamines and polycyclic aromatic ...

  5. Carcinogen - Wikipedia

    en.wikipedia.org/wiki/Carcinogen

    Aflatoxin B 1, a toxin produced by the fungus Aspergillus flavus which is a common contaminant of stored grains and nuts is a known cause of hepatocellular cancer. The bacteria H. Pylori is known to cause stomach cancer and MALT lymphoma. [24] Hepatitis B and C are associated with the development of hepatocellular cancer.

  6. Neoplasm - Wikipedia

    en.wikipedia.org/wiki/Neoplasm

    Tobacco smoke causes increased exogenous DNA damage, and these DNA damages are the likely cause of lung cancer due to smoking. [20] UV light from solar radiation causes DNA damage that is important in melanoma. [21] Helicobacter pylori infection produces high levels of reactive oxygen species that damage DNA and contributes to gastric cancer. [22]

  7. Warburg hypothesis - Wikipedia

    en.wikipedia.org/wiki/Warburg_hypothesis

    Scientist Otto Warburg, whose research activities led to the formulation of the Warburg hypothesis for explaining the root cause of cancer.. The Warburg hypothesis (/ ˈ v ɑːr b ʊər ɡ /), sometimes known as the Warburg theory of cancer, postulates that the driver of carcinogenesis (cancer formation) is insufficient cellular respiration caused by insult (damage) to mitochondria. [1]

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  9. Epidemiology of cancer - Wikipedia

    en.wikipedia.org/wiki/Epidemiology_of_cancer

    The epidemiology of cancer is the study of the factors affecting cancer, as a way to infer possible trends and causes. The study of cancer epidemiology uses epidemiological methods to find the cause of cancer and to identify and develop improved treatments. This area of study must contend with problems of lead time bias and length time bias ...