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The term "high dead space" refers to the fluid remaining within the needle and between the syringe hub and the plunger. This space can be as high as 84 micro liters in conventional syringes. [2] Conventional high dead space syringes have existed since the mass production of plastic syringes with removable needles in 1961. [3]
Regular insulin, also known as neutral insulin and soluble insulin, is a type of short-acting medical insulin. [2] It is used to treat type 1 diabetes , type 2 diabetes , gestational diabetes , and complications of diabetes such as diabetic ketoacidosis and hyperosmolar hyperglycemic states . [ 5 ]
Automatic syringes are known since the 1910s, [2] and many spring-loaded devices with needle protectors were patented in the first half of the 20th century, [3] but it was not until 1970s when they became economically feasible to mass-produce (simple syrettes were used instead before).
The dilution of insulin is such that 1 mL of insulin fluid has 100 standard "units" of insulin. [6] A typical insulin vial may contain 10 mL, for 1000 units. Insulin syringes are made specifically for a patient to inject themselves, and have features to assist this purpose when compared to a syringe for use by a healthcare professional: shorter ...
A standard insulin syringe with needle is smaller than an injector pen. Injector pens are an alternative to the manufacture of medication for injection in vials containing either liquid or a powder to which a diluent such as sterile water is added. When a vial is used as a means of storage, the end-user must use a syringe to "draw up" or remove ...
Jet injectors were used for mass vaccination, and as an alternative to needle syringes for diabetics to inject insulin. However, the World Health Organization no longer recommends jet injectors for vaccination due to risks of disease transmission. [1] Similar devices are used in other industries to inject grease or other fluid.