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  2. Unified Parkinson's disease rating scale - Wikipedia

    en.wikipedia.org/wiki/Unified_Parkinson's_disease...

    The unified Parkinson's disease rating scale (UPDRS) is used to follow the longitudinal course of Parkinson's disease. The UPD rating scale is the most commonly used scale in the clinical study of Parkinson's disease. [1] The UPDRS is made up of these sections: [2] Part I: evaluation of mentation, behavior, and mood

  3. Braak staging - Wikipedia

    en.wikipedia.org/wiki/Braak_staging

    A. Schematic initial progression of Lewy body deposits in the first stages of Parkinson's Disease, as proposed by Braak and colleagues. B. Localization of the area of significant brain volume reduction in initial PD compared with a group of participants without the disease in a neuroimaging study which concluded that brain stem damage may be the first identifiable stage of PD neuropathology. [1]

  4. Signs and symptoms of Parkinson's disease - Wikipedia

    en.wikipedia.org/wiki/Signs_and_symptoms_of...

    Parkinson's disease patient showing a typical flexed walking posture in advanced stage. Signs and symptoms of Parkinson's disease are varied. Parkinson's disease affects movement, producing motor symptoms. [1] Non-motor symptoms, which include dysautonomia, cognitive and neurobehavioral problems, and sensory and sleep difficulties, are also ...

  5. Hoehn and Yahr scale - Wikipedia

    en.wikipedia.org/wiki/Hoehn_and_Yahr_scale

    The Hoehn and Yahr scale is a commonly used system for describing how the symptoms of Parkinson's disease progress. It was originally published in 1967 in the journal Neurology by Margaret Hoehn and Melvin Yahr and included stages 1 through 5. [ 1 ]

  6. Parkinson-plus syndrome - Wikipedia

    en.wikipedia.org/wiki/Parkinson-plus_syndrome

    Parkinson-plus syndromes are usually more rapidly progressive and less likely to respond to antiparkinsonian medication than PD. [10] [11] However, the additional features of the diseases may respond to medications not used in PD. [citation needed] Current therapy for Parkinson-plus syndromes is centered around a multidisciplinary treatment of ...

  7. Animal models of Parkinson's disease - Wikipedia

    en.wikipedia.org/wiki/Animal_Models_of_Parkinson...

    Parkinson's disease is a neurodegenerative disorder, characterized by the loss of dopaminergic neurons in the substantia nigra pars compacta (SNpc). The loss of the dopamine neurons in the brain, results in motor dysfunction, ultimately causing the four cardinal symptoms of PD: tremor, rigidity, postural instability, and bradykinesia . [ 1 ]

  8. Management of Parkinson's disease - Wikipedia

    en.wikipedia.org/wiki/Management_of_Parkinson's...

    In the management of Parkinson's disease, due to the chronic nature of Parkinson's disease (PD), a broad-based program is needed that includes patient and family education, support-group services, general wellness maintenance, exercise, and nutrition. At present, no cure for the disease is known, but medications or surgery can provide relief ...

  9. List of diagnostic classification and rating scales used in ...

    en.wikipedia.org/wiki/List_of_diagnostic...

    The following diagnostic systems and rating scales are used in psychiatry and clinical psychology.This list is by no means exhaustive or complete. For instance, in the category of depression, there are over two dozen depression rating scales that have been developed in the past eighty years.