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  2. PDE5 inhibitor - Wikipedia

    en.wikipedia.org/wiki/PDE5_inhibitor

    All PDE5 inhibitors are generally well tolerated. [1] The occurrence of side effects, or adverse drug reactions (ADRs), with PDE5 inhibitors depends on the dose and type of agent. [1] Headache is a very common ADR, occurring in >10% of patients. Other common ADRs include: dizziness, flushing, dyspepsia, nasal congestion or rhinitis. [6]

  3. cGMP-specific phosphodiesterase type 5 - Wikipedia

    en.wikipedia.org/wiki/CGMP-specific...

    The most commonly available PDE5 inhibitors are sildenafil (Viagra), [14] vardenafil (Levitra), [15] tadalafil (Cialis), [16] and avanafil (Stendra). [17] PDE5 inhibitors are not routinely prescribed as first line treatment for erectile dysfunction. This is as they cause unwanted side effects like hair loss, headache, and nausea (among others ...

  4. Discovery and development of phosphodiesterase 5 inhibitors

    en.wikipedia.org/wiki/Discovery_and_development...

    PDE5 inhibitors are generally well tolerated, with side effects including transient headaches, flushing, dyspepsia, congestion and dizziness. [3] There have also been reports of temporary vision disturbances with sildenafil and, to a lesser extent, vardenafil, and back and muscle pain with tadalafil. [3]

  5. Got Headaches from Viagra or Cialis? Here's Why & How to Treat It

    www.aol.com/got-headaches-viagra-cialis-heres...

    Sildenafil, tadalafil and other treatments for ED all belong to a class of medications called phosphodiesterase type 5 or PDE5 inhibitors, which dilate the blood vessels that supply blood to the ...

  6. How to Get Better Viagra Results in 2025 - AOL

    www.aol.com/better-viagara-results-2025...

    However, healthcare providers sometimes prescribe multiple PDE5 inhibitors at once to help optimize the effects of each medication for an individual case — usually as a compounded medication ...

  7. Your ED Pill Guide: Everything You Need to Know Before ... - AOL

    www.aol.com/ed-pill-guide-everything-know...

    These ED drugs belong to a class of medications called PDE5 inhibitors, short for phosphodiesterase type 5 inhibitors. They suppress PDE5 (an enzyme in the smooth muscle cells of your blood ...

  8. Phosphodiesterase inhibitor - Wikipedia

    en.wikipedia.org/wiki/Phosphodiesterase_inhibitor

    Phosphodiesterase-5. A phosphodiesterase inhibitor is a drug that blocks one or more of the five subtypes of the enzyme phosphodiesterase (PDE), thereby preventing the inactivation of the intracellular second messengers, cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP) by the respective PDE subtype(s).

  9. What Happens If You Take Viagra and You Don't Need It? - AOL

    www.aol.com/happens-viagra-dont-105800158.html

    Side Effects and Risks of Taking Viagra without ED. ... and a healthcare professional will explain that phosphodiesterase type 5 inhibitors aren’t growth hormones, ...