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Orlistat is used for the treatment of obesity. The amount of weight loss achieved with orlistat varies. In one-year clinical trials, between 35.5% and 54.8% of subjects achieved a 5% or greater decrease in body mass, although not all of this mass was necessarily fat. Between 16.4% and 24.8% achieved at least a 10% decrease in body fat. [4]
A meta-analysis estimated that Cesarean delivery rates increased with odds ratios of 1.5 among overweight, 2 among obese, and 3 among severely obese women, compared with normal weight pregnant women. [11] In addition, morbidly obese women who have not had children before are at increased risk of all–cause preterm deliveries.
It decreases LDL by 15–30% and raises HDL by 3–5%, with little effect on triglycerides, but can cause a slight increase. Bile acid sequestrants may cause gastrointestinal problems and may also reduce the absorption of other drugs and vitamins from the gut. Ezetimibe is a selective inhibitor of dietary cholesterol absorption.
Example of an unsaturated fat triglyceride (C 55 H 98 O 6).Left part: glycerol; right part, from top to bottom: palmitic acid, oleic acid, alpha-linolenic acid. A triglyceride (from tri-and glyceride; also TG, triacylglycerol, TAG, or triacylglyceride) is an ester derived from glycerol and three fatty acids. [1]
For adult women who are obese and are reproductively active, each unit increase in BMI over a BMI of 32 kg/m 2 is associated with a reduction of spontaneous conception rate by 5%. [8] Obesity and overweight among women of reproductive age have been associated with reduced success of conception and a higher risk of complications during pregnancy ...
In the body, stores of fat are referred to as adipose tissue. In these areas, intracellular triglycerides are stored in cytoplasmic lipid droplets. When lipase enzymes are phosphorylated, they can access lipid droplets and through multiple steps of hydrolysis, breakdown triglycerides into fatty acids and glycerol. Each step of hydrolysis leads ...
The rise in older-age pregnancies, up 900% over the past five decades, marks a shift in women who are waiting for financial or emotional stability before making the commitment to raise a child.
Hyperlipidemia is abnormally high levels of any or all lipids (e.g. fats, triglycerides, cholesterol, phospholipids) or lipoproteins in the blood. [2] The term hyperlipidemia refers to the laboratory finding itself and is also used as an umbrella term covering any of various acquired or genetic disorders that result in that finding. [3]