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  2. Chromosomal inversion - Wikipedia

    en.wikipedia.org/wiki/Chromosomal_inversion

    An inversion is a chromosome rearrangement in which a segment of a chromosome becomes inverted within its original position. An inversion occurs when a chromosome undergoes a two breaks within the chromosomal arm, and the segment between the two breaks inserts itself in the opposite direction in the same chromosome arm.

  3. Situs inversus - Wikipedia

    en.wikipedia.org/wiki/Situs_inversus

    Situs inversus (also called situs transversus or oppositus) is a congenital condition in which the major visceral organs are reversed or mirrored from their normal positions. . The normal arrangement of internal organs is known as situs solit

  4. Inversion (evolutionary biology) - Wikipedia

    en.wikipedia.org/wiki/Inversion_(evolutionary...

    Balanoglossus, an example of a Hemichordata, represents an "evolutionary link" between invertebrates and vertebrates. In addition to the simple observation that the dorsoventral axes of protostomes and chordates appear to be inverted with respect to each other, molecular biology provides some support for the inversion hypothesis.

  5. Structural variation in the human genome - Wikipedia

    en.wikipedia.org/wiki/Structural_variation_in...

    The products of this mechanism from the sequence repeats is depicted in Figure 2. A study was done on the olfactory receptor gene clusters where they questioned if there was an association between normal rearrangement of 8p and the repeated inverted sequences. The researchers observed that the rearrangement of chromosomes was actually caused by ...

  6. Gene conversion - Wikipedia

    en.wikipedia.org/wiki/Gene_conversion

    Biased gene conversion (BGC) occurs when one allele has a higher probability of being the donor than the other in a gene conversion event. For example, when a T:G mismatch occurs, it would be more or less likely to be corrected to a C:G pair than a T:A pair. This gives that allele a higher probability of transmission to the next generation.

  7. Human genetics - Wikipedia

    en.wikipedia.org/wiki/Human_genetics

    Human genetics is the study of inheritance as it occurs in human beings.Human genetics encompasses a variety of overlapping fields including: classical genetics, cytogenetics, molecular genetics, biochemical genetics, genomics, population genetics, developmental genetics, clinical genetics, and genetic counseling.

  8. Fusion gene - Wikipedia

    en.wikipedia.org/wiki/Fusion_gene

    The first fusion gene [1] was described in cancer cells in the early 1980s. The finding was based on the discovery in 1960 by Peter Nowell and David Hungerford in Philadelphia of a small abnormal marker chromosome in patients with chronic myeloid leukemia—the first consistent chromosome abnormality detected in a human malignancy, later designated the Philadelphia chromosome. [3]

  9. Left-right asymmetry - Wikipedia

    en.wikipedia.org/wiki/Left-right_asymmetry

    In developmental biology, left-right asymmetry (LR asymmetry) is the process in early embryonic development that breaks the normal symmetry in the bilateral embryo.In vertebrates, left-right asymmetry is established early in development at a structure called the left-right organizer (the name of which varies between species) and leads to activation of different signalling pathways on the left ...