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In organic chemistry, an azo coupling is an reaction between a diazonium compound (R−N≡N +) and another aromatic compound that produces an azo compound (R−N=N−R’).In this electrophilic aromatic substitution reaction, the aryldiazonium cation is the electrophile, and the activated carbon (usually from an arene, which is called coupling agent), serves as a nucleophile.
Ministries of health in several sub-Saharan African countries, including Zambia, Uganda, and South African, were reported to have begun planning health system reform including hospital accreditation before 2002. However, most hospitals in Africa are administered by local health ministries or missionary organizations without accreditation programs.
VCA, Inc., doing business as VCA Animal Hospitals, operates more than 1,000 animal hospitals in the US and Canada. [1] The company is based in Los Angeles , and was founded in 1986. [ 2 ] Until its acquisition by Mars Inc. in 2017, VCA traded on the NASDAQ under the ticker "WOOF".
The compound is obtained by azo coupling of aniline and acetoacetanilide or their derivatives. The class of compounds was discovered in Germany in 1909. The initially formed diazo compound tautomerizes to give a ketohydrazone, which features extended pi-conjugation.
The latter easily converts to zidovudine 4 (also known as azidothymidine or AZT), an important antiviral drug, used among others in the treatment of AIDS. [ 17 ] [ 18 ] [ 19 ] Another example of pharmaceutical application of DEAD-assisted Mitsunobu reaction is the synthesis of bis[(pivaloyloxy)methyl [PIVz] derivative of 2'-deoxy-5 ...
Azobenzene is a photoswitchable chemical compound composed of two phenyl rings linked by a N=N double bond.It is the simplest example of an aryl azo compound.The term 'azobenzene' or simply 'azo' is often used to refer to a wide class of similar compounds.
A nitrogen bound to both a good electrofuge and a good nucleofuge is known as a nitrenoid (for its resemblance to a nitrene). [2] Nitrenes lack a full octet of electrons are thus highly electrophilic; nitrenoids exhibit analogous behavior and are often good substrates for electrophilic amination reactions.
Azobilirubin is a coloured compound formed by the condensation of diazotized sulfanilic acid with bilirubin in the van den Bergh reaction. [1] The quantity of bilirubin in patients with jaundice can be determined by the formation of azobilirubin in the presence of methanol.