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Cardiac physiology or heart function is the study of healthy, unimpaired function of the heart: involving blood flow; myocardium structure; the electrical conduction system of the heart; the cardiac cycle and cardiac output and how these interact and depend on one another.
The wall of the heart is made up of three layers: epicardium, myocardium, and endocardium. [8] The heart pumps blood with a rhythm determined by a group of pacemaker cells in the sinoatrial node. These generate an electric current that causes the heart to contract, traveling through the atrioventricular node and along the conduction system of ...
The main pumps involved are: the sarcoplasmic reticulum Ca 2+-ATPase, which pumps Ca 2+ back into the SR, the Sarcolemmal sodium-calcium exchanger, which pumps one Ca 2+ out of the cell, in exchange for 3 sodium ions being pumped into the cell, the Sarcolemmal Ca 2+-ATPase, which uses ATP to pump Ca 2+ directly out of the cell and the ...
The conduction system consists of specialized heart muscle cells, situated within the myocardium. [3] There is a skeleton of fibrous tissue that surrounds the conduction system which can be seen on an ECG. Dysfunction of the conduction system can cause irregular heart rhythms including rhythms that are too fast or too slow.
Congenital heart defects are divided into two main groups: cyanotic heart defects and non-cyanotic heart defects, depending on whether the child has the potential to turn bluish in color. [100] The problems may involve the interior walls of the heart, the heart valves, or the large blood vessels that lead to and from the heart. [99]
In vertebrates, the circulatory system is a system of organs that includes the heart, blood vessels, and blood which is circulated throughout the body. [1] [2] It includes the cardiovascular system, or vascular system, that consists of the heart and blood vessels (from Greek kardia meaning heart, and Latin vascula meaning vessels).
Figure 3 shows the important ion channels involved in the cardiac action potential, the current (ions) that flows through the channels, their main protein subunits (building blocks of the channel), some of their controlling genes that code for their structure, and the phases that are active during the cardiac action potential.
The heart is a muscular organ situated in the mediastinum.It consists of four chambers, four valves, two main arteries (the coronary arteries), and the conduction system. The left and right sides of the heart have different functions: the right side receives de-oxygenated blood through the superior and inferior venae cavae and pumps blood to the lungs through the pulmonary artery, and the left ...