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  2. RICE chart - Wikipedia

    en.wikipedia.org/wiki/RICE_chart

    The fourth row, labeled E, is the sum of the first two rows and shows the final concentrations of each species at equilibrium. It can be seen from the table that, at equilibrium, [H +] = x. To find x, the acid dissociation constant (that is, the equilibrium constant for acid-base dissociation) must be specified.

  3. Charlot equation - Wikipedia

    en.wikipedia.org/wiki/Charlot_equation

    The Henderson–Hasselbalch equation assumes that the autoionization of water is negligible and that the dissociation or hydrolysis of the acid and the base in solution are negligible (in other words, that the formal concentration is the same as the equilibrium concentration). For an acid-base equilibrium such as HA ⇌ H + + A −, the Charlot ...

  4. Acid dissociation constant - Wikipedia

    en.wikipedia.org/wiki/Acid_dissociation_constant

    In water, measurable pK a values range from about −2 for a strong acid to about 12 for a very weak acid (or strong base). A buffer solution of a desired pH can be prepared as a mixture of a weak acid and its conjugate base. In practice, the mixture can be created by dissolving the acid in water, and adding the requisite amount of strong acid ...

  5. Free base - Wikipedia

    en.wikipedia.org/wiki/Free_base

    However, since blood is buffered with carbonate at physiological pH (near 7.4), free-base amines will be rapidly converted back into their acid form. In fact, 94.19% of cocaine will exist as the acid form under equilibrium at pH=7.4, calculated using the Henderson–Hasselbalch equation assuming a pKa of 8.61.

  6. Henderson–Hasselbalch equation - Wikipedia

    en.wikipedia.org/wiki/Henderson–Hasselbalch...

    The equilibrium constant for the protonation of a base, B, + H + ⇌ + is an association constant, K b, which is simply related to the dissociation constant of the conjugate acid, BH +. = The value of is ca. 14 at 25 °C. This approximation can be used when the correct value is not known.

  7. Chemical reaction - Wikipedia

    en.wikipedia.org/wiki/Chemical_reaction

    The equilibrium is determined by the acid and base dissociation constants (K a and K b) of the involved substances. A special case of the acid-base reaction is the neutralization where an acid and a base, taken at the exact same amounts, form a neutral salt. Acid-base reactions can have different definitions depending on the acid-base concept ...

  8. Bjerrum plot - Wikipedia

    en.wikipedia.org/wiki/Bjerrum_plot

    3 (i.e. the first acid dissociation constant for carbonic acid), K 2 is the equilibrium constant for the reaction HCO − 3 ⇌ H + + CO 2− 3 (i.e. the second acid dissociation constant for carbonic acid), and DIC is the (unchanging) total concentration of dissolved inorganic carbon in the system, i.e. [CO 2] + [HCO − 3] + [CO 2− 3].

  9. Acid–base reaction - Wikipedia

    en.wikipedia.org/wiki/Acidbase_reaction

    In chemistry, an acidbase reaction is a chemical reaction that occurs between an acid and a base.It can be used to determine pH via titration.Several theoretical frameworks provide alternative conceptions of the reaction mechanisms and their application in solving related problems; these are called the acidbase theories, for example, Brønsted–Lowry acidbase theory.