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The primary side effect of phenylephrine is high blood pressure. People with high blood pressure are typically advised to avoid products containing it. Because this medication is a sympathomimetic amine without β-adrenergic receptor agonist activity, it does not increase contractility force and output of the cardiac muscle.
It is one of the preferred treatments for high blood pressure in pregnancy. [1] For other types of high blood pressure including very high blood pressure resulting in symptoms other medications are typically preferred. [1] It can be given by mouth or injection into a vein. [1] Onset of effects is around 5 hours and they last about a day. [1]
The choice between the drugs is to a large degree determined by the characteristics of the patient being prescribed for, the drugs' side effects, and cost. Most drugs have other uses; sometimes the presence of other symptoms can warrant the use of one particular antihypertensive. Examples include: Age can affect the choice of medications.
Guanfacine, sold under the brand name Tenex (immediate-release) and Intuniv (extended-release) among others, is an oral alpha-2a agonist medication used to treat attention deficit hyperactivity disorder (ADHD) and high blood pressure. [3] [10] Common side effects include sleepiness, constipation, and dry mouth. [10] Other side effects may ...
Rilmenidine, an oxazoline compound with antihypertensive properties, acts on both medullary and peripheral vasomotor structures.. Rilmenidine is a imidazoline analog and shows greater selectivity for imidazoline receptors than for cerebral alpha2-adrenergic receptors, distinguishing it from reference alpha2-agonists, and conferring additional anti-inflammatory actions not shared with most ...
Side effects of phenylpropanolamine include increased heart rate and blood pressure. [13] [14] [15] [12] Rarely, PPA has been associated with hemorrhagic stroke. [11] [16] [13] PPA acts as a norepinephrine releasing agent, indirectly activating adrenergic receptors. [17] [18] [19] As such, it is an indirectly acting sympathomimetic.