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The eclipse period is a variable period starting from HIV exposure in which no existing test can detect HIV. The median duration of the eclipse period in one study was 11.5 days. The window period is the time between HIV exposure and when an antibody or antigen test can detect HIV. The median window period for antibody/antigen testing is 18 days.
Structure of the RNA genome of HIV-1. The RNA genome consists of at least seven structural landmarks (LTR, TAR, RRE, PE, SLIP, CRS, and INS), and nine genes (gag, pol, and env, tat, rev, nef, vif, vpr, vpu, and sometimes a tenth tev, which is a fusion of tat, env and rev), encoding 19 proteins.
Trugene HIV-1 Genotyping Kit and Open Gene DNA Sequencing System [26] HIV-1 Genotyping: Patient monitoring: 4/24/2002: Siemens Medical Solutions Diagnostics Berkeley, CA ViroSeq HIV-1 Genotyping System with the 3700 Genetic Analyzer [27] HIV-1 Genotyping: Patient monitoring: 6/11/2003: Celera Diagnostics Alameda, CA Versant HIV-1 RNA 3.0 [28 ...
Viral load is reported as copies of HIV RNA in a millilitre (mL) of blood. Changes in viral load are usually reported as a log change (in powers of 10). For example, a three log increase in viral load (3 log10) is an increase of 10 3 or 1,000 times the previously reported level, while a drop from 500,000 to 500 copies would be a three-log-drop ...
P24 is a structural protein that plays a crucial role in the formation and stability of the viral capsid, which protects the viral RNA. p24 capsid protein's roles in the HIV replicative process are summarized as follows: [citation needed] Fusion: HIV replication cycle begins when HIV fuses with the surface of the host cell.
Non-reactive (negative) tests are followed up with nucleic acid tests for viral RNA. [27] About 70-80% of people infected with HIV will experience symptoms during the seroconversion period within about two to four weeks, primarily associated with a high viral load and the immune system's acute response to the infection. [25]