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Spinal and bulbar muscular atrophy; Spinal cord injury; Spinal cord tumors; Spinal muscular atrophy; Spinal muscular atrophy with respiratory distress type 1 – see Distal spinal muscular atrophy type 1; Spinocerebellar ataxia; Split-brain; Steele–Richardson–Olszewski syndrome – see Progressive supranuclear palsy; Stiff-person syndrome ...
The cause of the majority of spinal tumors is currently not known. Primary spinal tumors are associated with a few genetic syndromes. [1] [5] Neurofibromas are associated with neurofibromatosis 1 (NF1). [1] Meningiomas and schwannomas are associated with neurofibromatosis 2 (NF2). [1] Intramedullary hemangioblastomas can be seen in patients ...
Moderate-to-severe cases can cause radicular pain in the legs caused by nerve root compression. [5] The symptoms are usually exacerbated by upright posture and often, but not always, relieved by lying down. Postural headaches can be related to spontaneous spinal cerebrospinal fluid leaks. [6] However, in many patients, dural ectasia is ...
In addition to spinal stenosis, other lower back conditions such as spondylosis, tumors, infections and herniated or ruptured discs can cause NC. These conditions contribute to the potential narrowing of the spinal cord, increasing pressure and inducing damage on the spinal nerve roots, thus, causing paing, tingling or weakness in the lower body.
Causes can be bone fragments from a vertebral fracture, a tumor, abscess, ruptured intervertebral disc or other lesion. When acute it can cause a medical emergency independent of its cause, and require swift diagnosis and treatment to prevent long-term disability due to irreversible spinal cord injury .
Spinal tumors can be classified into primary tumours or metastatic tumours which originate from or disseminate to the site of compression, respectively. As the tumours surrounding the spinal column grow in size, the spinal canal is narrowed and therefore results in pressure to be exerted directly on the spinal cord and nerve roots.
Because each vertebra can cause pain in different areas of the body, the pain from the disease can be sensed in the back, leg, neck area, or even the arms. When the spinal canal begins to lose its gap and gets thinner, it can cause pain in the neck, which can also cause a numb feeling in the arms and hands.
Spinal stenosis occurs in as many as 8% of people. [4] It occurs most commonly in people over the age of 50. [9] Males and females are affected equally often. [10] The first modern description of the condition is from 1803 by Antoine Portal, and there is evidence of the condition dating back to Ancient Egypt. [11]