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Use during pregnancy or breastfeeding does not appear to be harmful to the fetus. [4] [6] [7] It can be used in children and those over 65 years of age. [4] Those with kidney problems may require a decrease in dose. [4] Cefalexin was developed in 1967. [8] [9] [10] It was first marketed in 1969 under the brand name Keflex.
Its use during pregnancy is contraindicated, although it has been placed in Australian pregnancy category C. [13] Its use during the first trimester (during organogenesis) and 12 weeks prior to pregnancy has been associated with an increased risk of congenital malformations, especially malformations associated with maternal folic acid ...
[108] [107] Cephalexin or nitrofurantoin are typically used because they are generally considered safe in pregnancy. [107] A kidney infection during pregnancy may result in preterm birth or pre-eclampsia (a state of high blood pressure and kidney dysfunction during pregnancy that can lead to seizures ). [ 42 ]
The β-lactam core structures. (A) A penam.(B) A carbapenam.(C) An oxapenam.(D) A penem.(E) A carbapenem.(F) A monobactam.(G) A cephem.(H) A carbacephem.(I) An oxacephem. This is a list of common β-lactam antibiotics—both administered drugs and those not in clinical use—organized by structural class.
β-Lactam antibiotics are indicated for the prevention and treatment of bacterial infections caused by susceptible organisms. At first, β-lactam antibiotics were mainly active only against gram-positive bacteria, yet the recent development of broad-spectrum β-lactam antibiotics active against various gram-negative organisms has increased their usefulness.
In Arkansas, state health officials announced a stunning statistic for 2023: The total number of abortions in the state, where some 1.5 million women live, was zero. In nearly a dozen states with ...
Nevertheless, during pregnancy, colonization can be temporary, intermittent, or continual. [12] Because of this the GBS colonization status of women can change during pregnancy, only cultures carried out ≤5 weeks before delivery and predict quite accurately the GBS carrier status at delivery. [62]
Data source: Yahoo Finance. YOY = year over year. The case to sell Costco stock. There's a lot to like about Costco, with all indications that its outlook is as strong as ever, supported by solid ...