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  2. Decitabine - Wikipedia

    en.wikipedia.org/wiki/Decitabine

    Decitabine (i.e., 5-aza-2′-deoxycytidine), sold under the brand name Dacogen among others, acts as a nucleic acid synthesis inhibitor. [4] It is a medication for the treatment of myelodysplastic syndromes, a class of conditions where certain blood cells are dysfunctional, and for acute myeloid leukemia (AML). [5] Chemically, it is a cytidine ...

  3. Hypomethylating agent - Wikipedia

    en.wikipedia.org/wiki/Hypomethylating_agent

    A hypomethylating agent (or demethylating agent [1]) is a drug that inhibits DNA methylation: the modification of DNA nucleotides by addition of a methyl group.Because DNA methylation affects cellular function through successive generations of cells without changing the underlying DNA sequence, treatment with a hypomethylating agent is considered a type of epigenetic therapy.

  4. Demethylating agent - Wikipedia

    en.wikipedia.org/wiki/Demethylating_agent

    Azacitidine and decitabine are marketed as Vidaza and Dacogen respectively. Azacitidine is the first drug to be approved by FDA for treating MDS and has been given orphan drug status. [ 2 ] [ 3 ] Procaine is a DNA-demethylating agent with growth-inhibitory effects in human cancer cells. [ 4 ]

  5. Losing Weight After 50 Is Possible: 21 Effective Tips From ...

    www.aol.com/losing-weight-50-possible-21...

    “There are myriad commonly used medications that promote weight gain, including diabetes medication, antidepressants, and high blood pressure medications,” says M. Daniela Hurtado, M.D., Ph.D ...

  6. Decitabine/cedazuridine - Wikipedia

    en.wikipedia.org/wiki/Decitabine/cedazuridine

    Decitabine/cedazuridine is indicated for treatment of adults with myelodysplastic syndromes, including previously treated and untreated, de novo and secondary myelodysplastic syndromes with the following French American-British subtypes (refractory anemia, refractory anemia with ringed sideroblasts, refractory anemia with excess blasts, and chronic myelomonocytic leukemia) and intermediate-1 ...

  7. Azacitidine - Wikipedia

    en.wikipedia.org/wiki/Azacitidine

    Azacitidine is a chemical analogue of the nucleoside cytidine, which is present in DNA and RNA.It is thought to have antineoplastic activity via two mechanisms – at low doses, by inhibiting of DNA methyltransferase, causing hypomethylation of DNA, [16] and at high doses, by its direct cytotoxicity to abnormal hematopoietic cells in the bone marrow through its incorporation into DNA and RNA ...

  8. Red Dye 3 Just Got Banned. These Are the Foods to Avoid If ...

    www.aol.com/red-dye-3-just-got-134800003.html

    The FDA’s recent ban on Red Dye No. 3, set to take effect by 2027 for foods and 2028 for drugs, marks a significant step in addressing safety concerns over artificial food dyes in the U.S. food ...

  9. Denise Austin, 67, Shares Her Top Exercise Secrets for Women ...

    www.aol.com/denise-austin-67-shares-her...

    Denise Austin shares her go-to “low-impact” exercises for women over 50. “The more muscles you use, the more calories you burn,” Austin tells Prevention . Plus, the “top-of-the-line ...

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