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Topical tac is a topical anesthetic solution [1] introduced by Pryor et al. in 1980. It is a mixture of 5 to 12% tetracaine, 0.05% adrenaline, and 4 or 10% cocaine hydrochloride (hence the "TAC" nomenclature).
This is a list of local anesthetic agents. Not all of these drugs are still used in clinical practice and in research. Some are primarily of historical interest ...
Many local anesthetics fall into two general chemical classes, amino esters (top) and amino amides (bottom). A local anesthetic (LA) is a medication that causes absence of all sensation (including pain) in a specific body part without loss of consciousness, [1] providing local anesthesia, as opposed to a general anesthetic, which eliminates all sensation in the entire body and causes ...
Local anesthetics vary in their pharmacological properties and they are used in various techniques of local anesthesia such as: Topical anesthesia (surface) - Similar to topical gel numbing before getting injected with Lidocaine. Infiltration; Plexus block; Adverse effects depend on the local anesthetic method and site of administration ...
Procaine is a local anesthetic drug of the amino ester group. It is most commonly used in dental procedures to numb the area around a tooth [1] and is also used to reduce the pain of intramuscular injection of penicillin. Owing to the ubiquity of the trade name Novocain or Novocaine, in some regions, procaine is referred to generically as ...
Chemistry, not moral failing, accounts for the brain’s unwinding. In the laboratories that study drug addiction, researchers have found that the brain becomes conditioned by the repeated dopamine rush caused by heroin. “The brain is not designed to handle it,” said Dr. Ruben Baler, a scientist with the National Institute on Drug Abuse.
The use of ketamine in anesthesia reflects its characteristics. It is a drug of choice for short-term procedures when muscle relaxation is not required. [34] The effect of ketamine on the respiratory and circulatory systems is different from that of other anesthetics. It suppresses breathing much less than most other available anesthetics. [35]
Because of the former use of cocaine as a local anesthetic, a suffix "-caine" was later extracted and used to form names of synthetic local anesthetics. Medicalization "Cocaine toothache drops", 1885 advertisement of cocaine for dental pain in children Advertisement in the January 1896 issue of McClure's Magazine for Burnett's Cocaine "for the ...