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High-grade prostatic intraepithelial neoplasia (HGPIN) is an abnormality of prostatic glands and believed to precede the development of prostate adenocarcinoma (the most common form of prostate cancer). [1] [2] It may be referred to simply as prostatic intraepithelial neoplasia (PIN).
A high-risk pregnancy is a pregnancy where the mother or the fetus has an increased risk of adverse outcomes compared to uncomplicated pregnancies. No concrete guidelines currently exist for distinguishing “high-risk” pregnancies from “low-risk” pregnancies; however, there are certain studied conditions that have been shown to put the mother or fetus at a higher risk of poor outcomes. [1]
Intrauterine growth restriction (IUGR), or fetal growth restriction, is the poor growth of a fetus while in the womb during pregnancy.IUGR is defined by clinical features of malnutrition and evidence of reduced growth regardless of an infant's birth weight percentile. [5]
Between 2010 and 2014, babies in the United States had an approximately 70% survival rate when born under weight of 500 g (1.10lb), an increase from a 30.8% survival rate between 2006 and 2010. [15] A baby's chances for survival increases 3 to 4 percentage points per day between 23 and 24 weeks of gestation, and about 2 to 3 percentage points ...
Requires a maternal blood draw. Based on DNA of fetal origin circulating in the maternal blood. Testing can potentially identify fetal aneuploidy [55] (available in the United States, beginning 2011) and gender of a fetus as early as six weeks into a pregnancy. Fetal DNA ranges from about 2–10% of the total DNA in maternal blood.
A BPP of 8 or 10 is generally considered reassuring. A BPP normally is not performed before the second half of a pregnancy since fetal movements do not occur in the first half. [ 5 ] The presence of these biophysical variables implies absence of significant central nervous system hypoxemia/acidemia at the time of testing.
The survival rate following treatment with chemotherapy is approximately at least 90%. [4] If gestational choriocarcinoma has spread to the liver in an individual, survival rate may be lower. [7] Overall survival rate is also higher when management of gestational choriocarcinoma occurs in a setting with physicians familiar with the condition.
Recently it has come to light that current growth charts for infants under 24 months overstate the expected weight of babies and lead to potentially obese children. This is because the original charts produced in 1977 were based on samples of middle-class white American babies on high-protein bottle-fed diets in Ohio.