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  2. Discovery and development of angiotensin receptor blockers

    en.wikipedia.org/wiki/Discovery_and_development...

    ARBs are blocking the last part of the renin–angiotensin pathway and block the pathway more specifically than ACE inhibitors. [1] The AT 1 receptor mediates Ang II to cause increased cardiac contractility, sodium reabsorption and vasoconstriction which all lead to increased blood pressure. By blocking AT 1 receptors, ARBs lead to lower blood ...

  3. Angiotensin II receptor blocker - Wikipedia

    en.wikipedia.org/wiki/Angiotensin_II_receptor...

    Losartan, the first ARB. Angiotensin II receptor blockers (ARBs), formally angiotensin II receptor type 1 (AT 1) antagonists, [1] also known as angiotensin receptor blockers, [2] [3] angiotensin II receptor antagonists, or AT 1 receptor antagonists, are a group of pharmaceuticals that bind to and inhibit the angiotensin II receptor type 1 (AT 1) and thereby block the arteriolar contraction and ...

  4. Antihypertensive - Wikipedia

    en.wikipedia.org/wiki/Antihypertensive

    Chronic kidney disease. ACEis or ARBs should be included in the treatment plan to improve kidney outcomes regardless of race or diabetic status. [7] [16] Late-stage dementia should consider deprescribing antihypertensives, according to the Medication Appropriateness Tool for Comorbid Health Conditions in Dementia (MATCH-D). [63] Diabetes mellitus.

  5. ACE inhibitor - Wikipedia

    en.wikipedia.org/wiki/ACE_inhibitor

    ACE inhibitors were initially approved for the treatment of hypertension and can be used alone or in combination with other anti-hypertensive medications. Later, they were found useful for other cardiovascular and kidney diseases [4] including: Acute myocardial infarction (heart attack) [5] Heart failure (left ventricular systolic dysfunction) [6]

  6. Drugs like Ozempic could protect kidney health in people with ...

    www.aol.com/drugs-ozempic-could-protect-kidney...

    Data from a new clinical trial suggest that people with obesity and cardiovascular disease who use semaglutide drugs, such as Ozempic and Wegovy, have a lower risk of adverse events related to ...

  7. ACE inhibitor and thiazide combination - Wikipedia

    en.wikipedia.org/wiki/ACE_inhibitor_and_thiazide...

    An ACE inhibitor and thiazide combination is a drug combination used to treat hypertension (high blood pressure). They are given by mouth.ACE inhibitors reduce the activity of angiotensin-converting enzyme (ACE) which produces angiotensin II, a hormone that constricts blood vessels.

  8. 5 car insurance myths — debunked: Red cars, rate negotiations ...

    www.aol.com/finance/car-insurance-myth-212820623...

    Myth #2: Your red car will cost more to insure. One of the most persistent myths about auto insurance is that insurance companies charge more to insure red cars.

  9. Angiotensin-converting enzyme 2 - Wikipedia

    en.wikipedia.org/wiki/Angiotensin-converting...

    59272 70008 Ensembl ENSG00000130234 ENSMUSG00000015405 UniProt Q9BYF1 Q8R0I0 RefSeq (mRNA) NM_021804 NM_001371415 NM_001130513 NM_027286 RefSeq (protein) NP_068576 NP_001358344 NP_001123985 NP_081562 Location (UCSC) Chr X: 15.56 – 15.6 Mb Chr X: 162.92 – 162.97 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Angiotensin-converting enzyme 2 (ACE2) is an enzyme that can be found ...

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