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The production of saliva is stimulated both by the sympathetic nervous system and the parasympathetic. [16] Sympathetic stimulation of saliva is to facilitate respiration, whereas parasympathetic stimulation is to facilitate digestion. Parasympathetic stimulation leads to acetylcholine (ACh) release onto the salivary acinar cells.
The salivary glands in many vertebrates including mammals are exocrine glands that produce saliva through a system of ducts. Humans have three paired major salivary glands (parotid, submandibular, and sublingual), as well as hundreds of minor salivary glands. [1] Salivary glands can be classified as serous, mucous, or seromucous (mixed).
The salivatory nuclei are pre-ganglionic parasympathetic neurons in the caudal pons representing the general visceral efferent (GVE) cranial nerve nuclei giving rise to axons which join (the intermediate nerve component of) the facial nerve (CN VII) and glossopharyngeal nerve (CN IX) to reach and innervate the salivary as well as lacrimal glands.
The parotid gland is a major salivary gland in many animals. In humans, the two parotid glands are present on either side of the mouth and in front of both ears. They are the largest of the salivary glands. Each parotid is wrapped around the mandibular ramus, and secretes serous saliva through the parotid duct into the mouth, to facilitate ...
The paired submandibular glands (historically known as submaxillary glands) are major salivary glands located beneath the floor of the mouth.In adult humans, they each weigh about 15 grams and contribute some 60–67% of unstimulated saliva secretion; on stimulation their contribution decreases in proportion as parotid gland secretion rises to 50%. [1]
Atropine - an antagonist. Muscarinic acetylcholine receptors, or mAChRs, are acetylcholine receptors that form G protein-coupled receptor complexes in the cell membranes of certain neurons [1] and other cells. They play several roles, including acting as the main end-receptor stimulated by acetylcholine released from postganglionic fibers.
The sympathetic nervous system's primary process is to stimulate the body's fight or flight response. It is, however, constantly active at a basic level to maintain homeostasis. [ 4 ] The sympathetic nervous system is described as being antagonistic to the parasympathetic nervous system. The latter stimulates the body to "feed and breed" and to ...
The glossopharyngeal nerve (/ ˌɡlɒsoʊfəˈrɪn (d) ʒiəl, - ˌfærənˈdʒiːəl / [1]), also known as the ninth cranial nerve, cranial nerve IX, or simply CN IX, [2] is a cranial nerve that exits the brainstem from the sides of the upper medulla, just anterior (closer to the nose) to the vagus nerve. Being a mixed nerve (sensorimotor), it ...