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Fat mass and obesity-associated protein, also known as alpha-ketoglutarate-dependent dioxygenase FTO, is an enzyme that in humans is encoded by the FTO gene located on chromosome 16. As one homolog in the AlkB family proteins, it is the first messenger RNA (mRNA) demethylase that has been identified. [ 5 ]
A group of 58 researchers is calling for a new, better way to measure obesity. The global team’s recommendations were published in The Lancet Diabetes & Endocrinology on Jan. 14. Body mass index ...
Set point theory does not on its own explain why body mass index for humans, measured as a proxy for fat, tends to change with increasing age or why obesity levels in a population vary depending on socioeconomic or environmental factors (or why weight tends to change for an individual when socioeconomic status and environment change). [4]
The science behind weight management is complex, but one of the key concepts that governs weight management is Energy Balance. [9] Energy Balance is the phrase used to describe the difference between the number of calories a person consumes and the number of calories that same person expends (a.k.a. burns) in a given time period. [9]
Osteoarthritis and obesity are closely linked. Obesity is one of the most important preventable factors for the development of osteoarthritis. Originally, the relationship between osteoarthritis and obesity was considered to be exclusively biomechanically based, according to which the excess weight caused the joint to become worn down more quickly.
An important link between genetics and obesity has just been discovered. Researchers from the University of British Columbia say by silencing a gene that codes for a certain protein, they cut fat ...
Obesity is one of the leading preventable causes of death worldwide. [38] [39] [40] The mortality risk is lowest at a BMI of 20–25 kg/m 2 [41] [37] [42] in non-smokers and at 24–27 kg/m 2 in current smokers, with risk increasing along with changes in either direction. [43] [44] This appears to apply in at least four continents. [42]
In one study, researchers told 10- to 12-year-olds all the genetic and medical factors that contribute to obesity. Afterward, the kids could recite back the message they received—fat kids didn’t get that way by choice—but they still had the same negative attitudes about the bigger kids sitting next to them.