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Sebaceous glands secrete the skin lubricant sebum. Sebum is secreted onto the hair shaft and it prevents the hair from splitting. It consists mostly of lipids. After the sebum spreads along and up the hair shaft, it is distributed over the skin surface where it lubricates and waterproofs the outer layer of the skin, the stratum corneum. [1] [2]
The sebaceous glands of a human fetus secrete a substance called vernix caseosa, a waxy, translucent white substance coating the skin of newborns. [7] After birth, activity of the glands decreases until there is almost no activity during ages two–six years, and then increases to a peak of activity during puberty , due to heightened levels of ...
Human skin pigmentation varies substantially between populations; this has led to the classification of people(s) on the basis of skin colour. [3] In terms of surface area, the skin is the second largest organ in the human body (the inside of the small intestine is 15 to 20 times larger).
The skin's protective acid mantle and lipid barrier sit on top of the stratum disjunctum. [5] The stratum disjunctum is the uppermost and loosest layer of skin. The stratum compactum is the comparatively deeper, more compacted and more cohesive part of the stratum corneum. [ 6 ]
The epidermis is the outermost of the three layers that comprise the skin, the inner layers being the dermis and hypodermis. [1] The epidermal layer provides a barrier to infection from environmental pathogens [2] and regulates the amount of water released from the body into the atmosphere through transepidermal water loss.
The dermis is composed of three major types of cells: [3] fibroblasts, macrophages, and mast cells.. Apart from these cells, the dermis is also composed of matrix components such as collagen (which provides strength), elastin (which provides elasticity), and extrafibrillar matrix, an extracellular gel-like substance primarily composed of glycosaminoglycans (most notably hyaluronan ...
Margaret Qualley's movie The Substance is having a moment, but for her, the repercussions lasted much longer. The skin on her face suffered the consequences of having regularly worn extensive ...
Human skin and its microbiota have a mutually beneficial symbiotic relationship, with the skin providing an optimal environment for resident microbiota while the microbiota help reinforce the skin's immunity by preventing colonization by harmful pathogens and contributing to skin acidification.