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Neurogenic bowel dysfunction (NBD) is reduced ability or inability to control defecation due to deterioration of or injury to the nervous system, resulting in fecal incontinence or constipation. [1] It is common in people with spinal cord injury (SCI), multiple sclerosis (MS) or spina bifida .
Fecal impaction is a common result of neurogenic bowel dysfunction and causes immense discomfort and pain. Its treatment includes laxatives, enemas, and pulsed irrigation evacuation (PIE) as well as digital removal. It is not a condition that resolves without direct treatment.
For example, certain cases of spinal cord injuries may sever key nerves necessary to maintain bladder and bowel control. The severance is often the cause of Neurogenic Bowel Dysfunction. [9] Similarly, spinal cord injuries can potentially cause a loss of motor control in lower limbs, such as with paraplegic and tetraplegic patients.
This page was last edited on 3 December 2024, at 08:41 (UTC).; Text is available under the Creative Commons Attribution-ShareAlike 4.0 License; additional terms may apply.
Bisacodyl is an organic compound that is used as a stimulant laxative drug. It works directly on the colon to produce a bowel movement. It is typically prescribed for relief of episodic and chronic constipation and for the management of neurogenic bowel dysfunction, as well as part of bowel preparation before medical examinations, such as for a colonoscopy.
Zeposia was approved by U.S. regulators for treating multiple sclerosis patients in March, but the drug became commercially available only on Monday as the COVID-19 pandemic delayed its launch.