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This is a list of adverse effects of the antidepressant trazodone, ... Rare (<0.1%) adverse effects include: Urinary retention; ... Extrapyramidal symptoms ...
Chemical structure of the prototypical Z-drug zolpidem. Nonbenzodiazepines (/ ˌ n ɒ n ˌ b ɛ n z oʊ d aɪ ˈ æ z ɪ p iː n,-ˈ eɪ-/ [1] [2]), sometimes referred to colloquially as Z-drugs (as many of their names begin with the letter "z"), are a class of psychoactive, depressant, sedative, hypnotic, anxiolytic drugs that are benzodiazepine-like in uses, such as for treating insomnia [3 ...
Trazodone. Doxepin. Zolpidem (Ambien) ... trazodone is an antidepressant that also works as a sedative and may be prescribed for insomnia. Trazodone ... but it can have intense side effects ...
Although it is hypothesized that somnifacients may help treat depression caused by insomnia, data released by the Food and Drug Administration (FDA) shows that the use of nonbenzodiazepines including zolpidem, zaleplon and eszopiclone increased the risk of depression by over two times when compared to individuals taking placebo pills. [23]
Zolpidem, sold under the brand name Ambien among others, is a medication primarily used for the short-term treatment of sleeping problems. [11] [16] Guidelines recommend that it be used only after cognitive behavioral therapy for insomnia and after behavioral changes, such as sleep hygiene, have been tried.
Trazodone lacks any affinity for the muscarinic acetylcholine receptors, so does not produce anticholinergic side effects. mCPP, a non-selective serotonin receptor modulator and serotonin releasing agent , is an active metabolite of trazodone and has been suggested to possibly play a role in its therapeutic benefits.