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This phenomenon can also be observed in adults who use the medication as a sleep aid. The prevalence of this paradoxical reaction is unknown, but research into the phenomenon suggests that it may be as a result of the medicine's interactions with the CYP2D6 enzyme, and that a metabolite of diphenhydramine may be to blame. [27]
Diphenhydramine is a first-generation antihistamine used to treat several conditions including allergic symptoms and itchiness, the common cold, insomnia, motion sickness, and extrapyramidal symptoms. [19] [20] Diphenhydramine also has local anesthetic properties, and has been used as such in people allergic to common local anesthetics such as ...
Paroxysmal nocturnal dyspnea is a serious medical symptom that can develop into worsening conditions. Many tests can be done in order to evaluate the cause of paroxysmal nocturnal dyspnea. Because it is commonly associated with heart failure, tests that may be run mainly focus on measuring the function and capability of the heart.
Two new studies indicate the importance of getting a good night's sleep — with one study saying a lack of sleep may be sabotaging the brain’s ability to keep intrusive thoughts at bay.
The first-generation sedating antihistamines diphenhydramine, doxepin, doxylamine, and pyrilamine are the most widely used medications in the world for preventing and treating insomnia. [6] As of 2004, doxylamine and diphenhydramine, which are both over-the-counter medications, were the agents most commonly used to treat short-term insomnia. [11]
If you got up early, it could simply be that you’d rather crawl under a blanket and watch Netflix than interact with other people—all of these are legitimate reasons to feel cranky during this ...
Magnesium-rich foods and beverages like whole grains, spinach, legumes, soymilk, and nuts and seeds can help you wake up feeling refreshed and get the most out of your travel experience.
Diphenhydramine is the primary constituent of dimenhydrinate and dictates the primary effect. The main differences relative to pure diphenhydramine are a lower potency due to being combined with 8-chlorotheophylline (by weight, dimenhydrinate is between 53% and 55.5% diphenhydramine) [10] and the fact that the stimulant properties of 8-chlorotheophylline help reduce the side ...