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  2. QT interval - Wikipedia

    en.wikipedia.org/wiki/QT_interval

    Prolonged QTc causes premature action potentials during the late phases of depolarization. This increases the risk of developing ventricular arrhythmias, including fatal ventricular fibrillation. [18] Higher rates of prolonged QTc are seen in females, older patients, high systolic blood pressure or heart rate, and short stature. [19]

  3. Long QT syndrome - Wikipedia

    en.wikipedia.org/wiki/Long_QT_syndrome

    Long QT syndrome is associated with a prolonged QTc, although in some genetically proven cases of LQTS this prolongation can be hidden, known as concealed LQTS. [23] The QTc is less than 450 ms in 95% of normal males, and less than 460 ms in 95% of normal females. LQTS is suggested if the QTc is longer than these cutoffs.

  4. Wikipedia:Osmosis/Long QT syndrome - Wikipedia

    en.wikipedia.org/wiki/Wikipedia:Osmosis/Long_QT...

    Long QT syndrome, or LQTS, is when somebody’s QT interval is longer than normal, which should typically be less than half of a cardiac cycle. In fact, for a heart rate of 60 beats per minute, the QT interval’s generally considered to be abnormally long when it’s greater than 440 milliseconds in males or 460 milliseconds in females.

  5. Drug-induced QT prolongation - Wikipedia

    en.wikipedia.org/wiki/Drug-induced_QT_prolongation

    The QTc interval is longer in females, as well as having a stronger response to IKr-blocking agents. In males, the presence of testosterone upregulates IKr channels and therefore decreases QT interval. [2] Stated otherwise, estrogens prolong the QT interval, while androgens shorten it and decrease the response to IKr-blocking agents. [citation ...

  6. Romano–Ward syndrome - Wikipedia

    en.wikipedia.org/wiki/Romano–Ward_syndrome

    Romano–Ward syndrome is associated with a prolonged QTc, although in some genetically proven cases of Romano–Ward syndrome this prolongation can be hidden, known as concealed Long QT syndrome. [13] The QTc is less than 450 ms in 95% of normal males, and less than 460 ms in 95% of normal females. Romano–Ward syndrome is suggested if the ...

  7. Jervell and Lange-Nielsen syndrome - Wikipedia

    en.wikipedia.org/wiki/Jervell_and_Lange-Nielsen...

    The cardiac features of JLNS can be diagnosed by measuring the QT interval corrected for heart rate (QTc) on a 12-lead electrocardiogram (ECG). The QTc is less than 450 ms in 95% of normal males, and less than 460 ms in 95% of normal females. In those with Jervell and Lange-Nielsen syndrome the QTc is typically greater than 500 ms. [8]

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  9. Electrocardiography - Wikipedia

    en.wikipedia.org/wiki/Electrocardiography

    A prolonged QTc interval is a risk factor for ventricular tachyarrhythmias and sudden death. Long QT can arise as a genetic syndrome, or as a side effect of certain medications. An unusually short QTc can be seen in severe hypercalcemia. <440 ms U wave: The U wave is hypothesized to be caused by the repolarization of the interventricular septum.