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Lifitegrast, sold under the brand name Xiidra (/ ˈ z aɪ d r ə / [2]), is a medication for the treatment of signs and symptoms of dry eye, a syndrome called keratoconjunctivitis sicca.
The tert-butyloxycarbonyl protecting group or tert-butoxycarbonyl protecting group [1] (BOC group) is an acid-labile protecting group used in organic synthesis. The BOC group can be added to amines under aqueous conditions using di- tert -butyl dicarbonate in the presence of a base such as sodium hydroxide :
Di-tert-butyl dicarbonate is a reagent widely used in organic synthesis. [1]Since this compound can be regarded formally as the acid anhydride derived from a tert-butoxycarbonyl (Boc) group, it is commonly referred to as Boc anhydride.
The procedure was pioneered by the Italian ophthalmic surgeon Professor Benedetto Strampelli [citation needed] in Rome in the early 1960s. The son of the geneticist and agronomist Nazareno Strampelli , Benedetto Strampelli held the chair of ophthalmic surgery at Rome's Ospedale di San Giovanni in Laterano where he was one of the first surgeons ...
A complete list of ophthalmic instruments can be found below: Instrument Uses Toric Marker: to mark 0 to 180 degree reference mark for Toric IOL implant Pre-chopper:
Rose bengal was originally prepared in 1882 by Swiss chemist Robert Ghnem, as an analogue of fluorescein. [4] Rudolf Nietzki at the University of Basel identified the principal constituents of rose bengal as iodine derivatives of di- and tetra-chlorofluorescein. [5]