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Several layers such as the neural tube, neural crest, surface ectoderm, and mesoderm contribute to the development of the eye. [2] [3] [4] Eye development is initiated by the master control gene PAX6, a homeobox gene with known homologues in humans (aniridia), mice (small eye), and Drosophila (eyeless). The PAX6 gene locus is a transcription ...
The surface ectoderm, AKA external ectoderm, is one of the two early embryonic divisions of the ectoderm. The other early division of the ectoderm is the neuroectoderm. The surface ectoderm develops into the following structures: Skin (only the epidermis; the dermis is derived from the mesoderm) (along with glands, hair, and nails)
1.1 Surface ectoderm. 1.1.1 Skin. 1.1.2 Anterior ... This is a list of cells in humans derived from the three embryonic germ layers – ectoderm, mesoderm, and ...
The eyes begin to develop as a pair of diverticula (pouches) from the lateral aspects of the forebrain.These diverticula make their appearance before the closure of the anterior end of the neural tube; [1] [2] after the closure of the tube around the 4th week of development, they are known as the optic vesicles.
In vertebrate embryos, the ectoderm can be divided into two parts: the dorsal surface ectoderm also known as the external ectoderm, and the neural plate, which invaginates to form the neural tube and neural crest. [4] The surface ectoderm gives rise to most epithelial tissues, and the neural plate gives rise to most neural tissues.
The ectoderm generates the outer layer of the embryo, and it forms from the embryo's epiblast. [13] The ectoderm develops into the surface ectoderm, neural crest, and the neural tube. [14] The surface ectoderm develops into: epidermis, hair, nails, lens of the eye, sebaceous glands, cornea, tooth enamel, the epithelium of the mouth and nose.
Bone morphogenic proteins are known to stimulate eye lens formation. During early development of eyes, the formation of the optic vesicle is essential in Mice and BMP4 expressed strongly in the optic vesicle and weakly in the surrounding mesenchyme and surface ectoderm. This concentration gradient of BMP4 in optic vesicle is critical for lens ...
The capsule is a very thick basement membrane [2] and the thickness varies in different areas on the lens surface and with the age of the animal. It is composed of various types of fibers such as collagen IV , [ 3 ] laminin , etc. [ 4 ] [ 5 ] [ 6 ] and these help it stay under constant tension. [ 7 ]