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Lipomas are rarely life-threatening, and the common subcutaneous lipomas are not a serious condition. Lipomas growing in internal organs can be more dangerous; for example, lipomas in the gastrointestinal tract can cause bleeding, ulceration, and painful obstructions (so-called "malignant by location", despite being a benign growth histologically).
Spindle cell lipoma is most frequently located in the upper back, shoulder, or posterior neck subcutaneous layer. [3] Nonetheless, reports of it occurring in the mediastinum, hypopharynx, larynx, anterior neck, suprasellar region, esophagus, nasal vestibule, tongue, floor of mouth, vallecula, parotid gland, and breast have been made. [4]
[10] [17] The fat deposited around the front of the neck is known as Madelung's collar or horse collar. [13] [5] Fat deposited on the back of the neck between the shoulder blades is known as a dorsocervical fat pad or buffalo hump. [13] [18] Fat deposited in the parotid region is known as hamster cheeks. [10]
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Lipomas affect about 1% of the population, with no documented sex bias, and about 1 in every 1000 people will have a lipoma within their lifetime. [25] [26] The cause of lipomas is not well defined. Genetic or inherited causes of lipomas play a role in around 2-3% of patients. [25]
Most cases of pleomorphic lipoma are seen in the subcutaneous tissue of the back, shoulder, and posterior neck. [2] Less commonly, it can also happen in odd places like the tongue, [3] vulva, [4] palm, [5] tonsillar fossa, [6] orbit, [7] and oral cavity. [8] The lesion usually presents as a subcutaneous lump that is circumscribed, like the ...
Some benign tumors are able to grow to a dangerous size because unlike other cells, “tumor cells have found a way to evade the normal life and death cycle of a cell — meaning they’ve learned ...
Other entities which are accompanied by multiple lipomas include Proteus syndrome, Cowden syndrome and related disorders due to PTEN gene mutations, benign symmetric lipomatosis (Madelung disease), Dercum's Disease, familial lipodystrophy, hibernomas, epidural steroid injections with epidural lipomatosis, [6] and familial angiolipomatosis.