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[1] [3] Other treatments may include medication to decrease the size of the prostate, urethral dilation, a urethral stent, or surgery. [1] Males are more often affected than females. [1] In males over the age of 40 about 6 per 1,000 are affected a year. [1] Among males over 80 this increases 30%. [1]
Benign prostatic hyperplasia (BPH), also called prostate enlargement, is a noncancerous increase in size of the prostate gland. [1] Symptoms may include frequent urination , trouble starting to urinate, weak stream, inability to urinate , or loss of bladder control . [ 1 ]
The side effects of bicalutamide, a nonsteroidal antiandrogen (NSAA), including its frequent and rare side effects, have been well-studied and characterized. The most common side effects of bicalutamide monotherapy in men include breast tenderness, breast growth, feminization, demasculinization, and hot flashes.
Dutasteride is used for treating BPH, colloquially known as an "enlarged prostate". [ 9 ] [ 14 ] It is approved by the Food and Drug Administration (FDA) in the U.S. for this indication. [ 15 ] A 2010 Cochrane review found a 25–26% reduction in the risk of developing prostate cancer with 5α-reductase inhibitor chemoprevention .
Flutamide has been researched and used extensively in the treatment of androgen-dependent skin and hair conditions in women including acne, seborrhea, hirsutism, and scalp hair loss, as well as in hyperandrogenism (e.g., in polycystic ovary syndrome or congenital adrenal hyperplasia), and is effective in improving the symptoms of these conditions.
Most men begin to produce less testosterone after age 30, with testosterone production dropping by about one percent every year. FYI: Women experience a similar drop in hormone levels, with ...